Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ATM | Q13315 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 2/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241522 | 0.89 | LMNA (0.37) | KDM4EATMHTTKMT2AMEN1 | |
| SCHEMBL11576098 | 0.84 | KDM4E (0.45) | KDM4EATMHTTKMT2AMEN1 | |
| SCHEMBL13777304 | 0.84 | KDM4E (0.39) | KDM4EATMHTTKMT2AMEN1 | |
| Bermoprofen SCHEMBL25434 | 0.84 | PTGS1 (0.49) | KMT2AMEN1HPGDABCC4PTGS1 | |
| SCHEMBL14434968 | 0.84 | PTGS1 (0.41) | KDM4EATMHTTKMT2AMEN1 | |
| Bermoprofen SCHEMBL29454489 | 0.84 | PTGS1 (0.49) | KMT2AMEN1HPGDABCC4PTGS1 | |
| SCHEMBL13875314 | 0.83 | PTGS1 (0.38) | KDM4EATMHTTKMT2AMEN1 | |
| Bermoprofen SCHEMBL11441448 | 0.82 | PTGS1 (0.39) | KDM4EATMRAD52ABCC4PTGS1 | |
| SCHEMBL11577980 | 0.78 | MAOB (0.40) | KDM4EATMHTTKMT2AMEN1 | |
| SCHEMBL11578024 | 0.76 | KDM4E (0.36) | KDM4EATMHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100217028-A1 | PROCESS FOR PREPARING NITROOXYALKYL SUBSTITUTED ESTERS OF CARBOXYLIC ACIDS, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | NICOX S.A. (FR) | 2010-08-26 | — | — | US | disclosed |
| US-20100137599-A1 | PROCESS FOR PREPARING 1,4-BUTANDIOL MONITRATE | NICOX S.A. (FR) | 2010-06-03 | — | — | US | disclosed |
| US-7723382-B2 | Process for preparing nitrooxyalkyl substituted esters of carboxylic acids, intermediates useful in said process and preparation thereof | NICOX S.A. (FR) | 2010-05-25 | — | — | US | disclosed |
| US-20070112194-A1 | Process for preparing nitrooxyalkyl substituted esters of carboxylic acids, intermediates useful in said process and preparation thereof | NICOX S.A. (FR) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137599-A1 | PROCESS FOR PREPARING 1,4-BUTANDIOL MONITRATE | CYP11B1, CYP11B2, HSD17B7 | KDM4E 1093/4885ATM 4513/4885HTT 3573/4885 |
| US-20100217028-A1 | PROCESS FOR PREPARING NITROOXYALKYL SUBSTITUTED ESTERS OF CARBOXYLIC ACIDS, INTERMEDIATES USEFUL IN SAID PROCESS AND PREPARATION THEREOF | CYP2A13, CYP3A43, POR | KDM4E 2469/4885ATM 3707/4885HTT 3987/4885 |
| US-20070112194-A1 | Process for preparing nitrooxyalkyl substituted esters of carboxylic acids, intermediates useful in said process and preparation thereof | CYP2A13, CYP3A43, POR | KDM4E 2469/4885ATM 3707/4885HTT 3987/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.