Bermoprofen

Bermoprofen

SCHEMBL25434

Cc1ccc2c(c1)CC(=O)c1cc(C(C)C(=O)O)ccc1O2

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 5/20 0.49
ABCC4 O15439 1/20 0.49
PTGS2 P35354 5/20 0.47
OPRK1 P41145 1/20 0.47
PDE4D Q08499 1/20 0.47
AKR1C3 P42330 7/20 0.40
AKR1C2 P52895 7/20 0.40
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
FABP2 P12104 1/20 0.36
TSHR P16473 1/20 0.36
AKR1C4 P17516 1/20 0.36
ADRA2B P18089 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2C P28335 1/20 0.36
DRD3 P35462 1/20 0.36
AKR1C1 Q04828 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bermoprofen SCHEMBL29454489 1.00 PTGS1 (0.49) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL14434968 0.93 PTGS1 (0.41) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL13875314 0.89 PTGS1 (0.38) PTGS1ABCC4PTGS2OPRK1PDE4D
Bermoprofen SCHEMBL11441448 0.88 PTGS1 (0.39) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11339446 0.86 PTGS2 (0.54) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL13241522 0.86 LMNA (0.37) PTGS1ABCC4MEN1KMT2ALMNA
SCHEMBL13220682 0.84 KDM4E (0.35) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11576098 0.81 KDM4E (0.45) MEN1KMT2AHPGD
SCHEMBL13777304 0.81 KDM4E (0.39) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11344285 0.80 PTGS1 (0.33) PTGS1ABCC4PTGS2OPRK1PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2971 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3706762-B1 N4-HYDROXYCYTIDINE DERIVATIVE AND ANTI-VIRAL USES RELATED THERETO UNIV EMORY (US) 2024-10-16 EP claimed
CN-118512401-A Lipid vesicle compositions with permeation enhancers 迪迪艾斯研究公司 2024-08-20 CN claimed
CN-118340907-A Polymer conjugates comprising bioactive agents 波利艾克蒂瓦有限公司 2024-07-16 CN claimed
CN-115175667-B Lipid vesicle compositions with permeation enhancers 迪迪艾斯研究公司 2024-06-04 CN claimed
US-20240041935-A1 PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS CREATIVE MEDICAL TECHNOLOGIES, INC. (US) 2024-02-08 US claimed
US-20220249467-A1 METHOD FOR IDENTIFYING TREATMENT OF INFECTIONS CAUSED BY PATHOGENS OF DIVERSE ORIGIN SYSTAMEDIC INC. (US) 2022-08-11 US claimed
EP-4034087-A1 LIPID VESICLE COMPOSITIONS WITH PENETRATION ENHANCING AGENTS DDS Research Inc. (CA) 2022-08-03 EP claimed
US-20220218611-A1 LIPID VESICLE COMPOSITIONS WITH PENETRATION ENHANCING AGENTS DDS RESEARCH INC. (CA) 2022-07-14 US claimed
EP-3998932-A1 ALKALIZATION OF URINARY BLADDER WALL PRIOR TO TREATMENT WITH INTRAVESICAL HEPARIN AND ALKALINIZED LIDOCAINE TO ENHANCE RELIEF OF BLADDER PAIN SYMPTOMS Parsons, C. Lowell (US) 2022-05-25 EP claimed
US-20210145763-A1 LOW THC HEMP EXTRACT AND METHOD OF TREATMENT OR PREVENTION OF AN EYE DISEASE EYE CO PTY LTD. (AU) 2021-05-20 US claimed
CN-1234792-A Nitrate ester derivatives and their use in the treatment of urinary incontinence and other disorders NICOX SA (FR) 1999-11-10 CN claimed
EP-0759899-B1 NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES NICOX SA (FR) 1999-09-15 EP claimed
EP-0931065-A2 NITRIC ESTER DERIVATIVES AND THEIR USE IN URINARY INCONTINENCE AND OTHER DISEASES NICOX S.A. (FR) 1999-07-28 EP claimed
WO-1998022114-A1 A METHOD FOR PROMOTING TISSUE REPAIR DUMEX-ALPHARMA A/S (DK) 1998-05-28 WO claimed
WO-1998009948-A2 NITRIC ESTER DERIVATIVES AND THEIR USE IN URINARY INCONTINENCE AND OTHER DISEASES NICOX S.A. (FR) 1998-03-12 WO claimed
EP-0759899-A1 NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES NICOX S.A. (FR) 1997-03-05 EP claimed
WO-1995030641-A1 NITRO COMPOUNDS AND THEIR COMPOSITIONS HAVING ANTI-INFLAMMATORY, ANALGESIC AND ANTI-THROMBOTIC ACITIVITIES NICOX S.A. (FR) 1995-11-16 WO claimed
EP-0003893-B1 NOVEL DIBENZ (B,F) OXEPIN AND DIBENZO (B,F) THIEPIN COMPOUNDS AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Dainippon Pharmaceutical Co., Ltd. (JP) 1981-11-04 EP claimed
US-4238620-A ANTIPYRETICS; ANALGESICS; ANTIINFLAMMATORY AGENTS DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1980-12-09 US claimed
EP-0003893-A1 Novel dibenz (b,f) oxepin and dibenzo (b,f) thiepin compounds and pharmaceutically acceptable salts thereof, processes for their preparation and pharmaceutical compositions containing them Dainippon Pharmaceutical Co., Ltd. (JP) 1979-09-05 EP claimed