Bermoprofen

Bermoprofen

SCHEMBL29454489

Cc1ccc2c(c1)CC(=O)c1cc(C(C)C(=O)O)ccc1O2

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 5/20 0.49
ABCC4 O15439 1/20 0.49
PTGS2 P35354 5/20 0.47
OPRK1 P41145 1/20 0.47
PDE4D Q08499 1/20 0.47
AKR1C3 P42330 7/20 0.40
AKR1C2 P52895 7/20 0.40
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
FABP2 P12104 1/20 0.36
TSHR P16473 1/20 0.36
AKR1C4 P17516 1/20 0.36
ADRA2B P18089 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2C P28335 1/20 0.36
DRD3 P35462 1/20 0.36
AKR1C1 Q04828 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bermoprofen SCHEMBL25434 1.00 PTGS1 (0.49) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL14434968 0.93 PTGS1 (0.41) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL13875314 0.89 PTGS1 (0.38) PTGS1ABCC4PTGS2OPRK1PDE4D
Bermoprofen SCHEMBL11441448 0.88 PTGS1 (0.39) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11339446 0.86 PTGS2 (0.54) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL13241522 0.86 LMNA (0.37) PTGS1ABCC4MEN1KMT2ALMNA
SCHEMBL13220682 0.84 KDM4E (0.35) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11576098 0.81 KDM4E (0.45) MEN1KMT2AHPGD
SCHEMBL13777304 0.81 KDM4E (0.39) PTGS1ABCC4PTGS2OPRK1PDE4D
SCHEMBL11344285 0.80 PTGS1 (0.33) PTGS1ABCC4PTGS2OPRK1PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4642771-A1 AMINE DERIVATIVES OF DIHYDRODIBENZO[b,f]OXEPINES AND METHOD OF PREPARATION THEREOF POLITECHNIKA WARSZAWSKA (PL) 2025-11-05 EP disclosed
US-20250304667-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN INC (US) 2025-10-02 US disclosed
EP-3693381-B1 LIGAND BINDING MOLECULES AND USES THEREOF VEGENICS PTY LTD (AU) 2025-09-03 EP disclosed
US-20250161402-A1 THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF DRY EYE DISEASE SCHEPENS EYE RES INST (US) 2025-05-22 US disclosed
CN-119947704-A Vapor deposition techniques for preparing pharmaceutical compositions 南爱克萨股份公司 2025-05-06 CN disclosed
CN-114716544-B Complement component C5 antibodies 阿勒根公司 2024-10-01 CN disclosed
US-20240301370-A1 Ligand Binding Molecules and Uses Thereof VEGENICS PTY LIMITED (AU) 2024-09-12 US disclosed
US-20240279317-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN INC (US) 2024-08-22 US disclosed
WO-2024162861-A1 AMINE DERIVATIVES OF DIHYDRODIBENZO[b,ƒ]OXEPINES AND METHOD OF PREPARATION THEREOF POLITECHNIKA WARSZAWSKA (PL) 2024-08-08 WO disclosed
US-20240189337-A1 NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF ASCLETIS BIOSCIENCE CO LTD (CN) 2024-06-13 US disclosed
US-11866739-B2 Ligand binding molecules and uses thereof VEGENICS PTY LIMITED (AU) 2024-01-09 US disclosed
US-11858999-B2 IL-17 receptor A antigen binding proteins AMGEN K-A, INC. (US) 2024-01-02 US disclosed
US-20230190782-A1 NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF ASCLETIS BIOSCIENCE CO., LTD. (CN) 2023-06-22 US disclosed
EP-4168092-A1 BALLOON CATHETER WITH PRECISION DRUG-ELUTING CAPABILITY C. R. Bard, Inc. (US) 2023-04-26 EP disclosed
US-20230124150-A1 COMPLEMENT FACTOR Bb ANTIBODIES ALLERGAN, INC. 2023-04-20 US disclosed
US-20220376763-A1 WIRELESS COMMUNICATION METHOD, DEVICE AND COMPUTER READABLE STORAGE MEDIUM THEREOF ZTE CORPORATION (CN) 2022-11-24 US disclosed
CN-114716544-A Complement component C5 antibody 阿勒根公司 2022-07-08 CN disclosed
EP-4008726-A1 COMPLEMENT COMPONENT C5 ANTIBODIES ALLERGAN, INC. (US) 2022-06-08 EP disclosed
CN-114502172-A Nucleoside prodrugs and related uses thereof 爱默蕾大学 2022-05-13 CN disclosed
US-20220088119-A1 THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF DRY EYE DISEASE SCHEPENS EYE RESEARCH INSTITUTE 2022-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220088119-A1 THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF DRY EYE DISEASE CRYAB, CRYAA, FUCA2 PTGS1 257/4885ABCC4 2455/4885PTGS2 313/4885
US-20240189337-A1 NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF TYMP, NUDT1, PNP PTGS1 1951/4885ABCC4 797/4885PTGS2 2545/4885
US-20230190782-A1 NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF TYMP, NUDT1, PNP PTGS1 1951/4885ABCC4 797/4885PTGS2 2545/4885
US-11858999-B2 IL-17 receptor A antigen binding proteins IL17A, IL23R, IL15RA PTGS1 3044/4885ABCC4 4121/4885PTGS2 3854/4885
US-20250161402-A1 THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF DRY EYE DISEASE CRYAB, CRYAA, FUCA2 PTGS1 257/4885ABCC4 2455/4885PTGS2 313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.