SCHEMBL1322232

SCHEMBL1322232

COc1ccc(C(c2ccccc2)(c2ccc(OC)cc2)C(O)[C@H]2O[C@@H](n3cnc4c3=NCN(C(=O)c3ccccc3)C=4N)C[C@@H]2OC(=O)CCC(=O)O)cc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10490993 0.77 HPGD (0.44) TYMP
SCHEMBL4434106 0.76 ADORA2A (0.39)
SCHEMBL1322252 0.74 POLB (0.53)
SCHEMBL1322836 0.73 RNASE1 (0.48)
SCHEMBL4553693 0.72 KDM4E (0.51) TYMP
SCHEMBL7879389 0.69 CHKA (0.36) TYMP
SCHEMBL7075967 0.69 ADORA2B (0.39)
SCHEMBL7070203 0.66 RNASE1 (0.47)
SCHEMBL7202899 0.66 ADORA2A (0.41)
Hydroquinone SCHEMBL7070523 0.65 PRMT6 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3059321-B1 MICROARRAY SYNTHESIS AND ASSEMBLY OF GENE-LENGTH POLYNUCLEOTIDES GEN9 INC (US) 2020-08-05 EP claimed
US-10450560-B2 Microarray synthesis and assembly of gene-length polynucleotides GEN9, INC. (US) 2019-10-22 US claimed
EP-3059321-A1 MICROARRAY SYNTHESIS AND ASSEMBLY OF GENE-LENGTH POLYNUCLEOTIDES Gen9, Inc. (US) 2016-08-24 EP claimed
US-20160001247-A1 MICROARRAY SYNTHESIS AND ASSEMBLY OF GENE-LENGTH POLYNUCLEOTIDES COMBIMATRIX CORPORATION 2016-01-07 US claimed
EP-1546387-B1 MICROARRAY SYNTHESIS AND ASSEMBLY OF GENE-LENGTH POLYNUCLEOTIDES GEN9 INC (US) 2016-01-06 EP claimed
EP-2330216-A1 Microarray synthesis and assembly of gene-length polynucleotides Gen9, Inc. (US) 2011-06-08 EP claimed
US-20100124767-A1 Microarray Synthesis and Assembly of Gene-Length Polynucleotides COMBIMATRIX CORPORATION (US) 2010-05-20 US claimed
US-7323320-B2 Microarray synthesis and assembly of gene-length polynucleotides COMBIMATRIX CORPORATION (US) 2008-01-29 US claimed
US-20060035218-A1 Microarray synthesis and assembly of gene-length polynucleotides GEN9, INC. 2006-02-16 US claimed
US-20050287585-A1 Microarray synthesis and assembly of gene-length polynucleotides GEN9, INC. 2005-12-29 US claimed
US-11629377-B2 Error detection during hybridisation of target double-stranded nucleic acid EVONETIX LTD (GB) 2023-04-18 US disclosed
EP-3688189-B1 ERROR DETECTION DURING HYBRIDISATION OF TARGET DOUBLE-STRANDED NUCLEIC ACID EVONETIX LTD (GB) 2022-05-04 EP disclosed
US-20210062185-A1 MICROARRAY SYNTHESIS AND ASSEMBLY OF GENE-LENGTH POLYNUCLEOTIDES GEN9, INC. (US) 2021-03-04 US disclosed
EP-3770270-A1 MICROASSAY SYNTHESIS AND ASSEMBLY OF GENE-LENGTH POLYNUCLEOTIDES Gen9, Inc. (US) 2021-01-27 EP disclosed
US-10774325-B2 Microarray synthesis and assembly of gene-length polynucleotides GEN9, INC. (US) 2020-09-15 US disclosed
US-20100124767-A1 Microarray Synthesis and Assembly of Gene-Length Polynucleotides COMBIMATRIX CORPORATION (US) 2010-05-20 US disclosed
US-7563600-B2 Microarray synthesis and assembly of gene-length polynucleotides COMBIMATRIX CORPORATION (US) 2009-07-21 US disclosed
US-7323320-B2 Microarray synthesis and assembly of gene-length polynucleotides COMBIMATRIX CORPORATION (US) 2008-01-29 US disclosed
US-20060035218-A1 Microarray synthesis and assembly of gene-length polynucleotides GEN9, INC. 2006-02-16 US disclosed
US-20050287585-A1 Microarray synthesis and assembly of gene-length polynucleotides GEN9, INC. 2005-12-29 US disclosed