Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | UBE2M | P61081 | 2/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.50 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | GRK5 | P34947 | 1/20 | 0.48 |
| ▸ | CDK8 | P49336 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467218 | 0.85 | OPRL1 (0.55) | SIGMAR1CHRM4KCNH2UBE2MDCUN1D1 | |
| SCHEMBL3037271 | 0.81 | CCR2 (0.45) | KCNH2 | |
| SCHEMBL3034202 | 0.81 | CCR2 (0.45) | KCNH2 | |
| SCHEMBL3029479 | 0.81 | CCR2 (0.45) | KCNH2CACNA1I | |
| SCHEMBL13222974 | 0.80 | CCR2 (0.47) | KCNH2CACNA1I | |
| SCHEMBL13222995 | 0.79 | CCR2 (0.43) | SIGMAR1KCNH2CACNA1I | |
| SCHEMBL3038616 | 0.79 | TACR1 (0.47) | SIGMAR1UBE2MDCUN1D1 | |
| SCHEMBL13222999 | 0.79 | CCR2 (0.45) | — | |
| SCHEMBL18657812 | 0.79 | SIGMAR1 (0.65) | SIGMAR1CHRM4UBE2MDCUN1D1 | |
| SCHEMBL3034250 | 0.78 | FAAH (0.44) | KCNH2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | CCR2, CCR1, CCR5 | SIGMAR1 374/4885CHRM4 506/4885KCNH2 4417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.