Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.34 |
| ▸ | FNTB | P49356 | 3/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | HRH1 | P35367 | 3/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696340 | 0.68 | VHL (0.34) | RAB9ALMNAMAPTTDP1 | |
| SCHEMBL13535017 | 0.67 | VHL (0.36) | IDO1NPC1MEN1LMNAMAPT | |
| SCHEMBL11471692 | 0.64 | CACNB4 (0.47) | HTR2CHTR2AHTR2BDRD2HRH1 | |
| SCHEMBL28166968 | 0.64 | DRD2 (0.44) | PGRHTR2CDRD2HRH1DRD4 | |
| 1,4-Dichlorobenzene SCHEMBL27455358 | 0.63 | MAPK1 (0.53) | IDO1CYP3A4TSHRLMNATDP1 | |
| SCHEMBL13812102 | 0.63 | IDO1 (0.42) | HTR2CHTR2AHTR2BIDO1DRD2 | |
| Hydrochloric Acid SCHEMBL11474191 | 0.63 | CACNB4 (0.46) | TP53CYP1A2TSHRCYP2C19MAPT | |
| SCHEMBL18748423 | 0.62 | S100A4 (0.41) | HTR2BTP53CYP1A2MEN1MAPT | |
| SCHEMBL14781250 | 0.61 | HTR2C (0.44) | HTR2CHTR2AHTR2BDRD2HRH1 | |
| Propionaldehyde SCHEMBL27792856 | 0.61 | CHRM2 (0.44) | CYP1A2TSHRKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197657-A1 | 2-ARYL OR HETEROARYL INDOLE DERIVATIVES | CHANG RONALD K | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100197657-A1 | 2-ARYL OR HETEROARYL INDOLE DERIVATIVES | ASIC1, ASIC3, TRPV1 | FNTA 3156/4885FNTB 3632/4885PGGT1B 1526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.