Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13232185 | 0.82 | ELANE (0.38) | KMT2APIK3CDBRD4ELANEBACE1 | |
| SCHEMBL13232203 | 0.81 | PKM (0.36) | PIK3CDELANEBACE1ALDH1A1 | |
| SCHEMBL13262626 | 0.68 | ITGB2 (0.32) | ELANECNR1HTT | |
| SCHEMBL13232197 | 0.67 | LMNA (0.35) | KDM4EMEN1KMT2ACNR1ALDH1A1 | |
| SCHEMBL1818959 | 0.67 | GAA (0.35) | KDM4EMEN1KMT2ABRD4ELANE | |
| SCHEMBL1821237 | 0.67 | NOX4 (0.34) | KDM4EMEN1KMT2AELANEBACE1 | |
| SCHEMBL1824112 | 0.67 | BACE1 (0.37) | MEN1KMT2AELANEBACE1ALDH1A1 | |
| SCHEMBL1818287 | 0.67 | IDH1 (0.34) | MEN1KMT2APIK3CDELANEBACE1 | |
| SCHEMBL1818288 | 0.67 | IDH1 (0.34) | MEN1KMT2APIK3CDELANEBACE1 | |
| SCHEMBL1818957 | 0.67 | GAA (0.35) | KDM4EMEN1KMT2ABRD4ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| WO-2009000757-A1 | PIPERAZINE COMPOUNDS WITH HERBICIDAL ACTION | BASF SE (DE) | 2008-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100167933-A1 | Piperazine Compounds With Herbicidal Action | PRXL2A, CBR1, CBR3 | ATM 4359/4885KDM4E 3601/4885CYP1A2 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.