SCHEMBL25548534

SCHEMBL25548534

CC1(C)OB(c2ccc3ccc4ccc5nn(-c6ccccc6)nc5c4c3c2)OC1(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
LPL P06858 2/20 0.39
LIPG Q9Y5X9 2/20 0.39
IDO1 P14902 1/20 0.38
TDO2 P48775 1/20 0.38
IRAK4 Q9NWZ3 1/20 0.36
EGFR P00533 2/20 0.36
PRMT5 O14744 1/20 0.35
WDR77 Q9BQA1 1/20 0.35
KDM4E B2RXH2 5/20 0.34
ALDH1A1 P00352 4/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
STAT1 P42224 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25548553 0.77 ALOX5 (0.48) ALOX5KDM4EALDH1A1NPC1RAB9A
SCHEMBL21128297 0.75 IDO1 (0.43) LPLLIPGIDO1TDO2IRAK4
SCHEMBL25548535 0.74 ADORA3 (0.46) ALOX5KDM4EALDH1A1NPC1RAB9A
SCHEMBL352617 0.74 LPL (0.40) LPLLIPGPRMT5WDR77KDM4E
SCHEMBL23753688 0.74 LPL (0.55) LPLLIPGIDO1TDO2IRAK4
SCHEMBL30565011 0.74 LPL (0.55) LPLLIPGIDO1TDO2IRAK4
SCHEMBL28509734 0.73 ALOX5 (0.43) ALOX5LPLLIPGIDO1TDO2
SCHEMBL25548138 0.72 ALOX5 (0.43) ALOX5KDM4EALDH1A1NPC1RAB9A
SCHEMBL20006903 0.72 LPL (0.53) LPLLIPGKDM4EHPGDP4HB
SCHEMBL29517937 0.72 LIPG (0.48) LPLLIPGIDO1TDO2IRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-06-01 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-18 US disclosed
US-20230140609-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-05-04 US disclosed
US-20230125329-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE MATERIAL, ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) 2023-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230140609-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885LPL 2338/4885LIPG 2947/4885
US-20230167089-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885LPL 2338/4885LIPG 2947/4885
US-20230134923-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885LPL 2338/4885LIPG 2947/4885
US-20230157161-A1 ORGANIC MATERIAL COMPOSITION AND APPLICATIONS THEREOF PIEZO1, VCL, VDAC3 ALOX5 977/4885LPL 2338/4885LIPG 2947/4885
US-20230125329-A1 COMPOUND, ORGANIC ELECTROLUMINESCENCE MATERIAL, ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE PIEZO1, EPCAM, L1CAM ALOX5 1610/4885LPL 1712/4885LIPG 1840/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.