Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | AKT2 | P31751 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13222016 | 0.82 | AKT1 (0.56) | AKT1AKT2TDP1KDM4EPKM | |
| SCHEMBL21998533 | 0.81 | AKT1 (0.66) | AKT1AKT2TDP1KDM4EPKM | |
| SCHEMBL19162664 | 0.79 | AKT1 (0.57) | AKT1AKT2TDP1KDM4EPKM | |
| SCHEMBL13439269 | 0.78 | MAPT (0.39) | AKT1AKT2TDP1KDM4EL3MBTL1 | |
| SCHEMBL15134436 | 0.78 | L3MBTL1 (0.51) | AKT1AKT2TDP1KDM4EPKM | |
| SCHEMBL18869688 | 0.75 | GPR3 (0.47) | TDP1KDM4EALDH1A1KMT2AGAA | |
| SCHEMBL14127894 | 0.75 | KDM4E (0.41) | KDM4EPKML3MBTL1ALDH1A1LMNA | |
| SCHEMBL12146712 | 0.74 | AKT1 (0.49) | AKT1AKT2TDP1KDM4EPKM | |
| SCHEMBL12146718 | 0.74 | AKT1 (0.49) | AKT1AKT2TDP1KDM4EPKM | |
| SCHEMBL3588444 | 0.73 | HPGD (0.53) | AKT1AKT2TDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10263193-B2 | Heterocyclic compound and organic light-emitting element using same | LG CHEM, LTD. (KR) | 2019-04-16 | — | — | US | disclosed |
| US-20100216725-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10263193-B2 | Heterocyclic compound and organic light-emitting element using same | CRY1, NFE2L2, CRY2 | AKT1 3753/4885AKT2 4116/4885TDP1 3618/4885 |
| US-20100216725-A1 | 4-AMINO-4-OXOBUTANOYL PEPTIDES AS INHIBITORS OF VIRAL REPLICATION | ZC3HAV1, VIP, O60361 | AKT1 3181/4885AKT2 3949/4885TDP1 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.