Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20299887 | 0.90 | TAS1R3 (0.45) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL28940166 | 0.90 | TAS1R3 (0.45) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL13245474 | 0.88 | GAA (0.57) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL13245482 | 0.87 | TAS1R3 (0.51) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL13245366 | 0.86 | TAS1R3 (0.52) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL13245384 | 0.85 | TAS1R3 (0.51) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL15227743 | 0.83 | RAB9A (0.44) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL13245485 | 0.81 | TAS1R3 (0.46) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL13245479 | 0.81 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A | |
| SCHEMBL19684300 | 0.80 | TAS1R3 (0.40) | L3MBTL1ALDH1A1TAS1R3TAS1R1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | L3MBTL1 2488/4885ALDH1A1 687/4885TAS1R3 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.