Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247764 | 0.86 | L3MBTL1 (0.37) | CACNA1GCACNA1BCACNA1CKDM4EMAPT | |
| SCHEMBL13248095 | 0.85 | HIF1A (0.38) | HIF1AITGB1ITGA4ALDH1A1L3MBTL1 | |
| SCHEMBL13248098 | 0.81 | CACNA1G (0.39) | CACNA1GCACNA1BCACNA1CNR1H2NR1H3 | |
| SCHEMBL4499651 | 0.79 | POLB (0.43) | MAPTLMNAPOLBALDH1A1L3MBTL1 | |
| SCHEMBL29943820 | 0.76 | BCL2A1 (0.39) | HIF1AITGB1ITGA4POLBGAA | |
| SCHEMBL4832843 | 0.76 | BCL2A1 (0.39) | HIF1AITGB1ITGA4POLBGAA | |
| SCHEMBL8313937 | 0.75 | SMN1; SMN2 (0.40) | ITGB1ITGA4LMNAALDH1A1L3MBTL1 | |
| SCHEMBL13248101 | 0.71 | NFKB1 (0.37) | MAPTHTTALDH1A1L3MBTL1 | |
| SCHEMBL4832911 | 0.70 | LMNA (0.41) | HIF1AKDM4EHTTLMNAPOLB | |
| SCHEMBL11531092 | 0.70 | CA2 (0.40) | ITGB1ITGA4ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087399-A1 | UROTENSIN-II RECEPTOR ANTAGONISTS | 第一三共株式会社 (JP) | 2010-08-05 | — | — | WO | disclosed |