Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306510 | 0.83 | TRPM4 (0.41) | TRPM4POLBG6PDKDM4EALDH1A1 | |
| SCHEMBL1306803 | 0.82 | HPGD (0.43) | TRPM4POLBG6PDKDM4EALDH1A1 | |
| SCHEMBL1326044 | 0.81 | TRPM4 (0.41) | TRPM4POLBG6PDKDM4EALDH1A1 | |
| SCHEMBL1306245 | 0.79 | HPGD (0.49) | TRPM4POLBKDM4EALDH1A1HPGD | |
| SCHEMBL1307208 | 0.79 | TRPM4 (0.41) | TRPM4POLBG6PDKDM4EALDH1A1 | |
| SCHEMBL1305803 | 0.79 | DHODH (0.43) | TRPM4POLBG6PDKDM4EALDH1A1 | |
| SCHEMBL1306695 | 0.79 | TRPM4 (0.42) | TRPM4POLBG6PDKDM4EALDH1A1 | |
| SCHEMBL1307100 | 0.78 | PTPN1 (0.45) | POLBALDH1A1HPGDHTTMEN1 | |
| SCHEMBL1306824 | 0.78 | L3MBTL1 (0.50) | POLBKDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL1306170 | 0.77 | ALDH1A1 (0.48) | POLBKDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |