Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30301228 | 1.00 | ALDH1A1 (0.53) | ALDH1A1GLADHFRKIF11TDP1 | |
| SCHEMBL619267 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GLADHFRTDP1CYP3A4 | |
| SCHEMBL1351843 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GLADHFRTDP1CYP3A4 | |
| SCHEMBL2997257 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GLADHFRTDP1CYP3A4 | |
| SCHEMBL29363243 | 0.83 | ALDH1A1 (0.53) | ALDH1A1GLADHFRTDP1CYP3A4 | |
| SCHEMBL3979543 | 0.82 | ALDH1A1 (0.51) | ALDH1A1GLADHFRTDP1CYP3A4 | |
| SCHEMBL28097894 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GLADHFRKIF11TDP1 | |
| SCHEMBL25385740 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GLADHFRTDP1CYP3A4 | |
| SCHEMBL31475708 | 0.79 | MEN1 (0.54) | ALDH1A1GLADHFRKIF11TDP1 | |
| SCHEMBL729501 | 0.78 | ALDH1A1 (0.65) | ALDH1A1GLADHFRTDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756057-B1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | CIPLA LTD (IN) | 2010-08-04 | — | — | EP | claimed |
| US-7705163-B2 | Process for the preparation of carvedilol | CIPLA LIMITED (IN) | 2010-04-27 | — | — | US | claimed |
| US-20080234492-A1 | Process for the Preparation of Carvedilol | CIPLA LIMITED (IN) | 2008-09-25 | — | — | US | claimed |
| EP-1756057-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | Cipla Ltd. (IN) | 2007-02-28 | — | — | EP | claimed |
| WO-2005113502-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | CIPLA LIMITED (IN) | 2005-12-01 | — | — | WO | claimed |
| CN-116042299-A | Antiwear lubricating oil and preparation method thereof | 徐武警 | 2023-05-02 | — | — | CN | disclosed |
| US-8058453-B2 | Process for the preparation of Carvedilol Form II | MATRIX LABORATORIES LTD. (IN) | 2011-11-15 | — | — | US | disclosed |
| EP-1756057-B1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | CIPLA LTD (IN) | 2010-08-04 | — | — | EP | disclosed |
| US-7705163-B2 | Process for the preparation of carvedilol | CIPLA LIMITED (IN) | 2010-04-27 | — | — | US | disclosed |
| US-7705163-B2 | Process for the preparation of carvedilol | CIPLA LIMITED (IN) | 2010-04-27 | — | — | US | disclosed |
| US-20090286991-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL FORM II | TIANISH LABORATORIES PRIVATE LIMITED (IN) | 2009-11-19 | — | — | US | disclosed |
| WO-2009115902-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL VIA SILYL PROTECTION OF SUBSTITUTED AMINE | CADILA PHARMACEUTICALS LTD. (IN) | 2009-09-24 | — | — | WO | disclosed |
| EP-1756057-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | Cipla Ltd. (IN) | 2007-02-28 | — | — | EP | disclosed |
| EP-1756057-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | Cipla Ltd. (IN) | 2007-02-28 | — | — | EP | disclosed |
| WO-2006060122-A9 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS INC (US) | 2006-08-17 | — | — | WO | disclosed |
| WO-2006060122-A2 | CARDIOTONIC COMPOUNDS WITH INHIBITORY ACTIVITY AGAINST BETA-ADRENERGIC RECEPTORS AND PHOSPHODIESTERASE | ARTESIAN THERAPEUTICS, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| WO-2005113502-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | CIPLA LIMITED (IN) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005113502-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL | CIPLA LIMITED (IN) | 2005-12-01 | — | — | WO | disclosed |
| WO-2004113296-A1 | A PROCESS FOR PREPARATION OF 1-[9H-CARBAZOL-4-YLOXY]- 3-[{2-(2-(-(METHOXY)PHENOXY)-ETHYL}-AMINO]-PROPAN-2-OL | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2004-12-29 | — | — | WO | disclosed |
| WO-1998009625-A1 | SELECTIVE β3 ADRENERGIC AGONISTS | ELI LILLY AND COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234492-A1 | Process for the Preparation of Carvedilol | ADRB2, ADRB3, ADRB1 | ALDH1A1 421/4885GLA 2151/4885DHFR 2735/4885 |
| US-20090286991-A1 | PROCESS FOR THE PREPARATION OF CARVEDILOL FORM II | ADRB2, ADRA2C, ADRB1 | ALDH1A1 931/4885GLA 1292/4885DHFR 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.