Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972321 | 0.87 | HTT (0.56) | HTTIDO1ALDH1A1MAPTALOX12 | |
| SCHEMBL7967903 | 0.85 | CNR1 (0.51) | HTTIDO1ALDH1A1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL7968560 | 0.84 | CNR1 (0.50) | HTTIDO1ALDH1A1MAPK1KMT2A | |
| SCHEMBL454852 | 0.83 | LMNA (0.50) | HTTALDH1A1MAPTALOX12PPARG | |
| SCHEMBL29373341 | 0.83 | LMNA (0.50) | HTTALDH1A1MAPTALOX12PPARG | |
| SCHEMBL7625975 | 0.81 | NPC1 (0.54) | HTTIDO1ALDH1A1LMNAMEN1 | |
| SCHEMBL8895176 | 0.81 | ALDH1A1 (0.53) | HTTIDO1ALDH1A1MAPTALOX12 | |
| SCHEMBL3980061 | 0.80 | LMNA (0.43) | HTTIDO1ALDH1A1MAPTALOX12 | |
| SCHEMBL9353428 | 0.80 | ALDH1A1 (0.43) | HTTIDO1ALDH1A1MAPTALOX12 | |
| Hydrochloric Acid SCHEMBL8896556 | 0.80 | ALDH1A1 (0.52) | HTTALDH1A1MAPTALOX12PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131877-B1 | BIGUANIDE COMPOUNDS | IMMUNOMET THERAPEUTICS INC (US) | 2023-07-19 | — | — | EP | disclosed |
| US-20170073331-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2017-03-16 | — | — | US | disclosed |
| US-20170073331-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | IMMUNOMET THERAPEUTICS INC. (US) | 2017-03-16 | — | — | US | disclosed |
| WO-2015160220-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | HANALL BIOPHARMA CO., LTD. (KR) | 2015-10-22 | — | — | WO | disclosed |
| CN-101141999-A | Oral care compositions containing free-b-ring flavonoids andflavans | COLGATE PALMOLIVE CO (US) | 2008-03-12 | — | — | CN | disclosed |
| EP-0422803-A2 | Dentifrice comprising cationic antibacterial agent | Beecham Group p.l.c. (GB) | 1991-04-17 | — | — | EP | disclosed |
| CN-1011287-B | oral hygiene preparation | ICI AMERICA INC (US) | 1991-01-23 | — | — | CN | disclosed |
| EP-0186276-B1 | ORAL HYGIENE COMPOSITION | ICI AMERICAS INC. (US) | 1990-11-22 | — | — | EP | disclosed |
| EP-0185971-B1 | USE OF ALKYLGLYCOSIDES AS POTENTIATORS IN ANTISEPTIC AGENTS, AND DISINFECTANT AND CLEARING AGENTS WITH A BACTERICIDAL ACTIVITY | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0074082-B1 | STABLE ORAL COMPOSITIONS CONTAINING ZINC AND FLUORIDE COMPOUNDS | Richardson-Vicks, Inc. (US) | 1987-10-21 | — | — | EP | disclosed |
| CN-85109119-A | ORAL HYGIENE COMPOSITION | — | 1986-08-27 | — | — | CN | disclosed |
| EP-0079611-A2 | Oral compositions containing strontium EDTA complex and soluble fluoride | Richardson-Vicks, Inc. (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0074082-A2 | Stable oral compositions containing zinc and fluoride compounds | Richardson-Vicks, Inc. (US) | 1983-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170073331-A1 | GUANIDINE COMPOUNDS AND USE THEREOF | PC, TFAM, PCK2 | HTT 399/4885IDO1 2222/4885ALDH1A1 1471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.