SCHEMBL249904

SCHEMBL249904

Cc1cc(C(C)(C)c2ccc(C(C)(c3cc(C)c(O)c(CO)c3)c3cc(C)c(O)c(CO)c3)cc2)cc(CO)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLF10 Q13118 1/20 0.53
SHBG P04278 1/20 0.46
ESR1 P03372 9/20 0.42
ALOX15 P16050 3/20 0.41
HTT P42858 2/20 0.41
MAPK1 P28482 1/20 0.41
ESR2 Q92731 7/20 0.40
CYP3A4 P08684 3/20 0.38
HPGD P15428 2/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 2/20 0.38
AR P10275 2/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
HTR6 P50406 1/20 0.38
ESRRG P62508 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CACNA1B Q00975 1/20 0.37
ALOX12 P18054 2/20 0.36
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2731014 0.94 KLF10 (0.51) KLF10SHBGESR1ALOX15HTT
SCHEMBL209020 0.93 KLF10 (0.59) KLF10SHBGESR1ALOX15HTT
SCHEMBL2618699 0.92 KLF10 (0.58) KLF10SHBGESR1ALOX15HTT
SCHEMBL10159934 0.89 KLF10 (0.51) KLF10SHBGESR1ALOX15HTT
SCHEMBL836696 0.88 SHBG (0.57) KLF10SHBGESR1ALOX15HTT
SCHEMBL31530701 0.88 SHBG (0.57) KLF10SHBGESR1ALOX15HTT
SCHEMBL25446800 0.87 KLF10 (0.53) KLF10SHBGESR1ALOX15HTT
SCHEMBL3451919 0.86 KLF10 (0.49) KLF10SHBGESR1ALOX15HTT
SCHEMBL3451808 0.86 KLF10 (0.51) KLF10ESR1ALOX15HTTMAPK1
SCHEMBL13257366 0.86 ESR1 (0.41) KLF10ESR1ALOX15HTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-RE43067-E1 Method for producing new polynuclear poly(formylphenol) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2012-01-03 US disclosed
US-7858819-B2 Tris(formylphenyl) and novel polynuclear phenol derived therefrom HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-12-28 US disclosed
US-7750190-B2 reacting hexamethylene tetramine in presence of acid; industrial scale; photoresists HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-07-06 US disclosed
US-20100099908-A1 TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2010-04-22 US disclosed
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2009-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182175-A1 METHOD FOR PRODUCING NEW POLYNUCLEAR POLY(FORMYLPHENOL) PCBP1, FPR2, PNKP KLF10 4594/4885SHBG 3146/4885ESR1 4141/4885
US-20100099908-A1 TRIS(FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED THEREFROM AS3MT, RRM2, SHROOM3 KLF10 2845/4885SHBG 1626/4885ESR1 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.