Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257579 | 0.92 | PDE7A (0.38) | PDE7AAPLNRALDH1A1MAPTHTT | |
| SCHEMBL13257621 | 0.86 | APLNR (0.48) | PDE7AAPLNRMAPTLMNATP53 | |
| SCHEMBL2993770 | 0.85 | FADS1 (0.36) | PDE7AALDH1A1MAPTHTTLMNA | |
| SCHEMBL13257600 | 0.85 | MAPT (0.37) | PDE7AAPLNRALDH1A1MAPTHTT | |
| SCHEMBL2565109 | 0.84 | FADS1 (0.47) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL13257587 | 0.84 | PDE7A (0.53) | PDE7AALDH1A1MAPTHTTLMNA | |
| SCHEMBL2990546 | 0.84 | TSHR (0.40) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL13258410 | 0.83 | ALDH1A1 (0.39) | PDE7AAPLNRALDH1A1HTTLMNA | |
| SCHEMBL3003982 | 0.83 | TSHR (0.39) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL13257584 | 0.82 | LMNA (0.42) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |