SCHEMBL13258155

SCHEMBL13258155

O=C(NNc1cc(C2=NOC(c3cc(Cl)cc(I)c3)(C(F)(F)F)C2)ccc1I)c1ccncc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
KCNMA1 Q12791 1/20 0.31
PKM P14618 2/20 0.30
KDM4E B2RXH2 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566577 0.88 GAA (0.36) MAPTSMN1; SMN2PKMKDM4E
SCHEMBL566693 0.80 GAA (0.36) MAPTSMN1; SMN2KDM4E
SCHEMBL10193736 0.79 CA1 (0.32)
SCHEMBL566034 0.78 GAA (0.40) MAPTSMN1; SMN2KCNMA1KDM4EL3MBTL1
SCHEMBL566017 0.76 GAA (0.39) MAPTSMN1; SMN2KDM4E
SCHEMBL566747 0.76 KMT2A (0.36) MAPTSMN1; SMN2KDM4EL3MBTL1
SCHEMBL28908198 0.74 ADCY1 (0.38) MAPTPKM
SCHEMBL10039199 0.74 MEN1 (0.45) MAPTSMN1; SMN2KDM4E
SCHEMBL1547546 0.74 BRAF (0.40) MAPT
SCHEMBL472295 0.74 CA1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010090344-A1 HYDRAZIDE COMPOUND AND USE OF THE SAME IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-12 WO disclosed