Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 10/20 | 0.43 |
| ▸ | CA2 | P00918 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563803 | 0.89 | TDP1 (0.47) | TDP1LMNATSHRPOLBKDM4E | |
| SCHEMBL6906218 | 0.81 | TSHR (0.40) | TDP1CA1CA2LMNATSHR | |
| SCHEMBL16982683 | 0.81 | TDP1 (0.52) | TDP1POLBSMN1; SMN2 | |
| SCHEMBL6907873 | 0.80 | LMNA (0.39) | CA1CA2LMNATSHRCA12 | |
| SCHEMBL6907851 | 0.79 | OPRM1 (0.43) | CA1CA2LMNATSHRCA12 | |
| SCHEMBL30069487 | 0.78 | TDP1 (0.69) | TDP1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL12321274 | 0.78 | GAA (0.40) | TDP1KDM4E | |
| SCHEMBL12321275 | 0.78 | ALDH1A1 (0.42) | LMNATSHRPOLBKDM4E | |
| SCHEMBL30580346 | 0.77 | TDP1 (0.58) | TDP1CA1CA2 | |
| SCHEMBL8597736 | 0.77 | TDP1 (0.58) | TDP1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210054001-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | HOWARD HUGHES MEDICAL INSTITUTE | 2021-02-25 | — | — | US | disclosed |
| WO-2010091126-A1 | XANTHENE DYES COMPRISING A SULFONAMIDE GROUP | BIOTIUM, INC. (US) | 2010-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210054001-A1 | BRIGHT TARGETABLE RED CA2+ INDICATORS | ATP2A2, ATP2A3, CACNB2 | TDP1 2934/4885CA1 47/4885CA2 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.