Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 18/20 | 0.56 |
| ▸ | ESR1 | P03372 | 10/20 | 0.56 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.42 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13257465 | 0.81 | ESR2 (0.54) | ESR2ESR1 | |
| SCHEMBL2565882 | 0.76 | PIK3CD (0.45) | TTBK1 | |
| SCHEMBL4462170 | 0.72 | ESR2 (0.72) | ESR2ESR1 | |
| SCHEMBL1795123 | 0.72 | ESR2 (1.00) | ESR2ESR1 | |
| SCHEMBL23505912 | 0.70 | PRKCI (0.43) | — | |
| SCHEMBL13257467 | 0.69 | ALDH1A1 (0.34) | ESR2ESR1TTBK1TTBK2 | |
| SCHEMBL13257531 | 0.69 | LMNA (0.44) | ESR2ESR1 | |
| SCHEMBL14038593 | 0.68 | ESR2 (0.78) | ESR2ESR1 | |
| SCHEMBL7014104 | 0.67 | PRKCI (0.40) | — | |
| SCHEMBL13257517 | 0.66 | LMNA (0.39) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |