Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 6/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13266571 | 0.82 | METAP2 (0.37) | — | |
| SCHEMBL2560728 | 0.81 | PIK3CD (0.46) | POLB | |
| SCHEMBL13257642 | 0.78 | PDE7A (0.51) | LMNAMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL13257534 | 0.76 | APLNR (0.49) | LMNAMAPK1 | |
| SCHEMBL13257531 | 0.75 | LMNA (0.44) | LMNAMAPK1ESR1ESR2ALDH1A1 | |
| SCHEMBL13258403 | 0.75 | ALDH1A1 (0.54) | LMNAMAPK1ESR1ESR2ALDH1A1 | |
| SCHEMBL13257678 | 0.74 | PDE11A (0.43) | LMNAMAPK1ESR1ESR2MEN1 | |
| SCHEMBL13257650 | 0.72 | LMNA (0.43) | LMNAMAPK1ESR1ESR2ALDH1A1 | |
| SCHEMBL13266380 | 0.71 | PDE10A (0.36) | ALDH1A1 | |
| SCHEMBL2561841 | 0.71 | PIK3CD (0.46) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087467-A1 | DELTA-5-DESATURASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-05 | — | — | WO | disclosed |