Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23129062 | 0.88 | MAPT (0.40) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL24160213 | 0.88 | THRB (0.38) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL23934357 | 0.88 | ALDH1A1 (0.37) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL23739877 | 0.87 | MAPT (0.38) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL20327290 | 0.86 | ALDH1A1 (0.35) | THRBPOLBALDH1A1MAPTLMNA | |
| SCHEMBL11888309 | 0.86 | ALOX15 (0.45) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL26289667 | 0.86 | KMT2A (0.37) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL12862399 | 0.86 | KDM4E (0.41) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL13258695 | 0.86 | THRB (0.38) | THRBGAAPOLBALDH1A1MAPT | |
| SCHEMBL23739470 | 0.84 | LMNA (0.36) | THRBGAAPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3725771-A1 | ALK PROTEIN DEGRADATION AGENT AND ANTI-TUMOR APPLICATION THEREOF | Shanghaitech University (CN) | 2020-10-21 | — | — | EP | disclosed |
| EP-3357513-A1 | PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Kangpu Biopharmaceuticals, Ltd. (CN) | 2018-08-08 | — | — | EP | disclosed |
| WO-2010093434-A1 | ISOTOPOLOGUES OF LENALIDOMIDE | CELGENE CORPORATION (US) | 2010-08-19 | — | — | WO | disclosed |