SCHEMBL1326311

SCHEMBL1326311

C=CCOCC(O)CC(N)CN1CCNC1=O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.40
PER2 O15055 4/20 0.38
CA1 P00915 4/20 0.37
CA2 P00918 4/20 0.37
CA7 P43166 4/20 0.37
CRY2 Q49AN0 1/20 0.35
CYP2D6 P10635 1/20 0.34
CA4 P22748 3/20 0.33
CA9 Q16790 3/20 0.33
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7853509 0.87 PER2 (0.45) POLBPER2CA1CA2CA7
SCHEMBL1902367 0.79 CA1 (0.40) POLBPER2CA1CA2CA7
SCHEMBL14364275 0.76 POLB (0.38) POLBPER2CA1CA2CA7
SCHEMBL98511 0.75 RAB9A (0.36) POLBPER2CA1CA2CA7
SCHEMBL1782980 0.75 RET (0.51) POLBPER2CA1CA2CA7
SCHEMBL27751229 0.70 POLB (0.38) POLBCA1CA2CA7CYP2D6
SCHEMBL21711061 0.69 PER2 (0.49) POLBPER2CRY2CYP2D6
SCHEMBL1628393 0.68 ALDH1A1 (0.39) POLBCYP2D6
SCHEMBL9427330 0.68 PER2 (0.44) POLBPER2CRY2CYP2D6
SCHEMBL1305192 0.68 CYP2D6 (0.38) POLBCA1CA2CA7CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003715-B Alcohol-soluble ink for printing plastic woven bags and preparation method thereof 山东华诺日化有限公司 2021-08-10 CN claimed
US-20110077365-A1 PREPARATION OF ORGANOSILICON-CONTAINING TRIAZOLES MCMASTER UNIVERSITY (CA) 2011-03-31 US claimed
US-7763268-B2 Load bearing hydrogel implants THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2010-07-27 US claimed
US-20100029789-A1 Load Bearing Hydrogel Implants THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2010-02-04 US claimed
US-6210783-B1 COMPRISED OF SUPPORTING SUBSTRATE, A HEAT DISSIPATING COATING LAYER IN CONTACT WITH SUBSTRATE, WHEREIN COATING IS COMPRISED OF A HEAT DISSIPATING BINDER, AN ANTISTATIC COMPOUND, AN INK RECEIVER COATING COMPRISING BINDER, OXAZOLINE COMPOUND XEROX CORPORATION 2001-04-03 US claimed
US-5919552-A Coated substrates and methods XEROX CORPORATION (US) 1999-07-06 US claimed
US-5908908-A EMULSION ACRYLIC INTERPOLYMER CONTAINING 05 TO 1% BY WEIGHT OF AT LEAST ONE (METH)ACRYLIC OR VINYL MONOMER CONTAINING A UREIDO GROUP ELF ATOCHEM S.A. (FR) 1999-06-01 US claimed
US-5885678-A IMAGES ON BOOK SPINES AND BOOK COVERS EXHIBIT REDUCED CURL AND HIGH DEGREE OF LIGHTFASTNESS AND WATERPROOFING XEROX CORPORATION (US) 1999-03-23 US claimed
US-5795695-A PHOTO-QUALITY RECORDING XEROX CORPORATION (US) 1998-08-18 US claimed
US-5763128-A Simulated photographic-quality images on a substrate without curl XEROX CORPORATION (US) 1998-06-09 US claimed
US-5759734-A Method of generating simulated photographic-quality images on luminescent melt-formed backing substrates XEROX CORPORATION (US) 1998-06-02 US claimed
US-5759727-A TONER IMAGE ON TRANSPARENT SUBSTRATE; MELT POLYMER BACKING XEROX CORPORATION (US) 1998-06-02 US claimed
US-5751432-A Highlight gloss for xerographic engine XEROX CORPORATION (US) 1998-05-12 US claimed
US-5746814-A Decurling compositions XEROX CORPORATION (US) 1998-05-05 US claimed
US-5744273-A Laminatable backing substrates containing fluoro compounds for improved toner flow XEROX CORPORATION (US) 1998-04-28 US claimed
US-5709976-A Coated papers XEROX CORPORATION (US) 1998-01-20 US claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5672424-A Ink jet transparencies XEROX CORPORATION (US) 1997-09-30 US claimed
CN-110003715-B Alcohol-soluble ink for printing plastic woven bags and preparation method thereof 山东华诺日化有限公司 2021-08-10 CN disclosed
US-5672424-A Ink jet transparencies XEROX CORPORATION (US) 1997-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077365-A1 PREPARATION OF ORGANOSILICON-CONTAINING TRIAZOLES ATR, RNF31, RNF5 POLB 3119/4885PER2 4747/4885CA1 2727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.