Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | OAT | P04181 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | IL1RN | P18510 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16423211 | 0.78 | KDM1A (0.38) | KDM1AMAOBMAOA | |
| SCHEMBL733324 | 0.73 | SLC18A3 (0.38) | ALDH1A1SIGMAR1 | |
| SCHEMBL14336758 | 0.70 | PLAU (0.41) | KDM1AMAOBPLAUSIGMAR1 | |
| Biphenyl SCHEMBL27474545 | 0.69 | ALDH1A1 (0.56) | KDM1AMAOBALDH1A1PLAUMAOA | |
| SCHEMBL7357477 | 0.68 | RAB9A (0.41) | ALDH1A1LMNA | |
| SCHEMBL23614560 | 0.65 | CYP11B2 (0.33) | ALDH1A1SIGMAR1 | |
| SCHEMBL8187300 | 0.65 | SLC18A3 (0.39) | ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7593570 | 0.65 | KDM1A (0.39) | KDM1AMAOBALDH1A1SIGMAR1 | |
| SCHEMBL18045066 | 0.65 | PLAU (0.45) | KDM1AMAOBALDH1A1PLAUMAOA | |
| SCHEMBL17257754 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754899-B2 | Method for producing optically active aziridine compounds and amine compounds as well as complexes and their intermediates used in this method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20080081916-A1 | Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081916-A1 | Method for Producing Optically Active Aziridine Compounds and Amine Compounds as Well as Complexes and their Intermadiates Used in this Method | INTS9, RAD54L, CD99 | KDM1A 1834/4885MAOB 23/4885OAT 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.