SCHEMBL1326472

SCHEMBL1326472

CCCCC/N=N/c1ccc(/C=C/c2ccc(/N=N/CCCCC)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4A O75164 4/20 0.37
KDM2A Q9Y2K7 4/20 0.37
AHR P35869 1/20 0.36
CYP2C9 P11712 3/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35
KCNH2 Q12809 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP19A1 P11511 1/20 0.33
CYP2C19 P33261 1/20 0.33
PTGS1 P23219 2/20 0.32
PTGS2 P35354 2/20 0.32
ALOX5 P09917 1/20 0.32
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
RELA Q04206 1/20 0.31
APP P05067 1/20 0.30
EGFR P00533 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1326473 1.00 KDM4A (0.37) KDM4AKDM2AAHRCYP2C9CYP3A4
SCHEMBL10597262 0.79 ESR1 (0.46) CYP3A4PTGS1PTGS2ALDH1A1KMT2A
SCHEMBL8726009 0.79 ESR1 (0.46) CYP3A4PTGS1PTGS2ALDH1A1KMT2A
SCHEMBL3432777 0.79 ALDH1A1 (0.44) CYP2C9CYP3A4CYP2D6CYP1A2CYP2C19
SCHEMBL3432776 0.79 ALDH1A1 (0.44) CYP2C9CYP3A4CYP2D6CYP1A2CYP2C19
SCHEMBL9332414 0.78
SCHEMBL9332407 0.78
SCHEMBL3195894 0.77 ALDH1A1 (0.42) KCNH2ALDH1A1KMT2ATP53SMN1; SMN2
SCHEMBL10431203 0.77 ALDH1A1 (0.42) KCNH2ALDH1A1KMT2ATP53SMN1; SMN2
SCHEMBL10431202 0.77 ALDH1A1 (0.42) KCNH2ALDH1A1KMT2ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0819305-B1 LIQUID CRYSTAL OPTICAL STORAGE MEDIUM WITH GRAY SCALE ELSICON INC (US) 2004-11-17 EP claimed
US-5846452-A Liquid crystal optical storage medium with gray scale ALLIANT TECHSYSTEMS INC. (US) 1998-12-08 US claimed
EP-0387059-B1 Process of aligning liquid crystal media HERCULES INC (US) 1998-06-10 EP claimed
EP-0819305-A1 LIQUID CRYSTAL OPTICAL STORAGE MEDIUM WITH GRAY SCALE ALLIANT TECHSYSTEMS INC. (US) 1998-01-21 EP claimed
WO-1996031876-A1 LIQUID CRYSTAL OPTICAL STORAGE MEDIUM WITH GRAY SCALE ALLIANT TECHSYSTEMS INC. (US) 1996-10-10 WO claimed
US-5032009-A Polarized light exposure HERCULES INCORPORATED (US) 1991-07-16 US claimed
US-4974941-A Process of aligning and realigning liquid crystal media HERCULES INCORPORATED (US) 1990-12-04 US claimed
EP-0387059-A2 Process of aligning liquid crystal media HERCULES INCORPORATED (US) 1990-09-12 EP claimed
US-12044872-B2 Method for generating alignment on top of a liquid crystal polymer material Rolic Technologies AG (CH) 2024-07-23 US disclosed
US-12012382-B2 Polymerizable liquid crystal having a carbazole core Rolic Technologies AG (CH) 2024-06-18 US disclosed
US-12006463-B2 Polymerizable liquid crystal having a quinoxaline-hydrazone core Rolic Technologies AG (CH) 2024-06-11 US disclosed
US-11952524-B2 Compositions of polymerizable liquid crystals Rolic Technologies AG (CH) 2024-04-09 US disclosed
EP-3175493-B1 ENCAPSULATION STRUCTURE FOR AN OLED DISPLAY INCORPORATING ANTIREFLECTION PROPERTIES BASF COATINGS GMBH (DE) 2024-03-06 EP disclosed
EP-3990568-B1 NEW POLYMERIZABLE LIQUID CRYSTAL HAVING A QUINOXALINE-HYDRAZONE CORE ROLIC TECH AG (CH) 2023-11-15 EP disclosed
EP-0445629-A2 Process of preparing liquid crystal compositions containing multiple oriented mesogens HERCULES INCORPORATED (US) 1991-09-11 EP disclosed
US-5032009-A Polarized light exposure HERCULES INCORPORATED (US) 1991-07-16 US disclosed
EP-0432735-A2 Liquid crystal coupled dichroic dyes HERCULES INCORPORATED (US) 1991-06-19 EP disclosed
EP-0406812-A2 Process for the preparation of NiNi-dialkyl-1,8-naphthalene diamine HERCULES INCORPORATED (US) 1991-01-09 EP disclosed
US-4974941-A Process of aligning and realigning liquid crystal media HERCULES INCORPORATED (US) 1990-12-04 US disclosed
EP-0387059-A2 Process of aligning liquid crystal media HERCULES INCORPORATED (US) 1990-09-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12012382-B2 Polymerizable liquid crystal having a carbazole core FZD7, CCL11, SGK2 KDM4A 2694/4885KDM2A 4006/4885AHR 2027/4885
US-12006463-B2 Polymerizable liquid crystal having a quinoxaline-hydrazone core AQP1, AQP4, HCN1 KDM4A 1647/4885KDM2A 2635/4885AHR 3269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.