Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13267485 | 0.87 | ANPEP (0.47) | ANPEP | |
| SCHEMBL10287224 | 0.87 | HPGDS (0.51) | ADAMTS5ALDH1A1NPC1LMNA | |
| SCHEMBL255220 | 0.86 | NPC1 (0.41) | NPC1 | |
| SCHEMBL13244783 | 0.86 | — | — | |
| SCHEMBL201374 | 0.86 | ANPEP (0.54) | ANPEPPTPN1MMP2MMP8MMP12 | |
| SCHEMBL405554 | 0.85 | TAS1R3 (0.50) | ANPEPALDH1A1HPGDNPC1LMNA | |
| SCHEMBL13266884 | 0.84 | EPHX2 (0.44) | — | |
| SCHEMBL13266970 | 0.83 | HDAC1 (0.44) | — | |
| SCHEMBL12361495 | 0.82 | PLK1 (0.48) | ANPEPMMP2ALDH1A1NPC1 | |
| SCHEMBL13267173 | 0.80 | MKNK1 (0.56) | NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | ACHAOGEN, INC. (US) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190766-A1 | ANTIBACTERIAL AGENTS | MRPL21, SI, ABCB11 | ANPEP 735/4885PTPN1 3039/4885MMP2 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.