Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909267 | 0.83 | KMT2A (0.53) | POLBHSD11B1TDP1MEN1KMT2A | |
| SCHEMBL8288851 | 0.83 | PREP (0.52) | PREPP2RX7 | |
| SCHEMBL27896422 | 0.81 | TDP1 (0.42) | POLBHSD11B1TDP1MEN1KMT2A | |
| SCHEMBL12031768 | 0.79 | PREP (0.50) | PREPP2RX7CHRNB1CHRNB2CHRNB4 | |
| SCHEMBL6265889 | 0.79 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL17600705 | 0.79 | LMNA (0.53) | POLBRAB9AHCRTR2HCRTR1 | |
| SCHEMBL17600704 | 0.79 | LMNA (0.53) | POLBRAB9AHCRTR2HCRTR1 | |
| SCHEMBL25796211 | 0.77 | L3MBTL1 (0.53) | PREPMEN1KMT2AALDH1A1CHRNB2 | |
| SCHEMBL7960177 | 0.77 | TDP1 (0.48) | POLBTDP1MEN1KMT2APDE2A | |
| SCHEMBL8635649 | 0.76 | PREP (0.45) | PREPPOLBHSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893573-B1 | INHIBITORS OF HCV REPLICATION | BRISTOL MYERS SQUIBB CO (US) | 2010-07-21 | — | — | EP | disclosed |