Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | PARL | Q9H300 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316486 | 0.79 | POLB (0.49) | POLBKDM4EALOX12LMNASMN1; SMN2 | |
| SCHEMBL13316487 | 0.76 | ALOX12 (0.51) | POLBKDM4EALOX12LMNASMN1; SMN2 | |
| SCHEMBL1710103 | 0.75 | ALOX12 (0.41) | POLBKDM4EALOX12LMNASMN1; SMN2 | |
| SCHEMBL16290005 | 0.74 | ALOX12 (0.53) | POLBKDM4EALOX12LMNASMN1; SMN2 | |
| SCHEMBL9189958 | 0.73 | — | — | |
| SCHEMBL17701589 | 0.73 | ALOX12 (0.34) | POLBKDM4EALOX12LMNASMN1; SMN2 | |
| SCHEMBL17194212 | 0.73 | ALOX12 (0.34) | POLBKDM4EALOX12LMNASMN1; SMN2 | |
| SCHEMBL4587864 | 0.71 | ALOX12 (0.47) | POLBKDM4EALOX12LMNASMN1; SMN2 | |
| SCHEMBL14789767 | 0.71 | MGLL (0.37) | LMNASMN1; SMN2MAPTMAPK1HPGD | |
| SCHEMBL784740 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150355201-A1 | FOLATE DERIVATIVES, USEFUL IN PARTICULAR IN THE CONTEXT OF THE FOLATE ASSAY | BIOMERIEUX (FR) | 2015-12-10 | — | — | US | disclosed |
| US-20150299244-A1 | TESTOSTERONE DERIVATIVES WITH A CARBOXYALKYL SUBSTITUTION IN POSITION 3 AND USE THEREOF FOR THE PRODUCTION OF LABELLED STEROIDS FOR DETERMINING THE CONCENTRATION OF TESTOSTERONE IN A BIOLOGICAL SAMPLE | BIOMERIEUX (FR) | 2015-10-22 | — | — | US | disclosed |
| WO-2010078202-A1 | CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME | UNIVERSITY OF MIAMI (US) | 2010-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150355201-A1 | FOLATE DERIVATIVES, USEFUL IN PARTICULAR IN THE CONTEXT OF THE FOLATE ASSAY | FOLR2, FOLR1, DHFR | POLB 673/4885KDM4E 3931/4885ALOX12 1391/4885 |
| US-20150299244-A1 | TESTOSTERONE DERIVATIVES WITH A CARBOXYALKYL SUBSTITUTION IN POSITION 3 AND USE THEREOF FOR THE PRODUCTION OF LABELLED STEROIDS FOR DETERMINING THE CONCENTRATION OF TESTOSTERONE IN A BIOLOGICAL SAMPLE | SHBG, CYP17A1, CYP21A2 | POLB 1146/4885KDM4E 1187/4885ALOX12 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.