Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18393768 | 0.70 | — | — | |
| SCHEMBL3373675 | 0.67 | — | — | |
| SCHEMBL22681717 | 0.66 | RXRA (0.49) | DAO | |
| SCHEMBL1778412 | 0.65 | ADRA1B (0.42) | DAOADRA1B | |
| SCHEMBL3372268 | 0.64 | DAO (0.31) | DAO | |
| SCHEMBL23707594 | 0.63 | RORC (0.37) | DAO | |
| SCHEMBL15998771 | 0.63 | TRPV1 (0.46) | DAOCSF1R | |
| SCHEMBL135636 | 0.63 | — | — | |
| SCHEMBL659645 | 0.63 | ALOX5 (0.36) | DAOADRA1B | |
| SCHEMBL4532127 | 0.63 | ALOX5 (0.36) | DAOADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2014-02-19 | — | — | EP | disclosed |
| WO-2012142513-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2012-10-18 | — | — | WO | disclosed |