Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705464 | 0.89 | ALDH1A1 (0.63) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL3709108 | 0.83 | SMN1; SMN2 (0.60) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL3718164 | 0.82 | SMN1; SMN2 (0.58) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL3706529 | 0.79 | ALDH1A1 (0.57) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL14375211 | 0.76 | ACHE (0.62) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL3709485 | 0.74 | FAAH (0.50) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL8821312 | 0.73 | KDM4E (0.62) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL14980282 | 0.73 | SMN1; SMN2 (0.69) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL3707768 | 0.72 | TSHR (0.51) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL3707708 | 0.72 | TSHR (0.51) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |