Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | ACACA | Q13085 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.45 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709871 | 0.90 | FAAH (0.60) | FAAHKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3705464 | 0.82 | ALDH1A1 (0.63) | FAAHKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3779080 | 0.80 | CHRM4 (0.56) | KDM4EALDH1A1SMN1; SMN2GPR119ACHE | |
| Hydrochloric Acid SCHEMBL3966170 | 0.79 | CHRM4 (0.55) | KDM4EALDH1A1SMN1; SMN2GPR119ACHE | |
| SCHEMBL3706529 | 0.78 | ALDH1A1 (0.57) | FAAHKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19297248 | 0.77 | GPR119 (0.53) | KDM4EGPR119MAPT | |
| SCHEMBL3709108 | 0.77 | SMN1; SMN2 (0.60) | FAAHKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3570582 | 0.76 | ACHE (0.61) | KDM4EALDH1A1SMN1; SMN2GPR119ACHE | |
| Hydrochloric Acid SCHEMBL3718164 | 0.76 | SMN1; SMN2 (0.58) | FAAHKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3715140 | 0.76 | IDE (0.57) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |