Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3709108 | 0.94 | SMN1; SMN2 (0.60) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL3718164 | 0.93 | SMN1; SMN2 (0.58) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL3706529 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL13283963 | 0.89 | KDM4E (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL8821312 | 0.83 | KDM4E (0.62) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL14375211 | 0.83 | ACHE (0.62) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL3709485 | 0.82 | FAAH (0.50) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL3707708 | 0.81 | TSHR (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL3707768 | 0.81 | TSHR (0.51) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 | |
| SCHEMBL23507365 | 0.81 | KDM4E (0.70) | ALDH1A1KDM4ELMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | claimed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010081851-A1 | PIPERIDIN-4-YLPIPERAZINE COMPOUNDS FOR THE TREATMENT OF HCV INFECTION | GENOSCIENCE PHARMA (FR) | 2010-07-22 | — | — | WO | disclosed |