Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 1/20 | 0.55 |
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | LTK | P29376 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14552117 | 0.93 | COMT (0.57) | COMTCKS1BSKP2TOP2ACCNA2 | |
| SCHEMBL10032425 | 0.91 | IKBKB (0.52) | COMTCKS1BSKP2TOP2AIKBKB | |
| SCHEMBL3289250 | 0.89 | PIK3CA (0.53) | COMTCKS1BSKP2TOP2AIKBKB | |
| SCHEMBL28859500 | 0.89 | IKBKB (0.53) | COMTCKS1BSKP2TOP2AIKBKB | |
| Benzene SCHEMBL28095234 | 0.89 | IKBKB (0.53) | COMTCKS1BSKP2TOP2AIKBKB | |
| SCHEMBL28868 | 0.89 | IKBKB (0.53) | COMTCKS1BSKP2TOP2AIKBKB | |
| SCHEMBL5467861 | 0.88 | KDM4E (0.50) | COMTCKS1BSKP2TOP2AMEN1 | |
| SCHEMBL4295175 | 0.87 | IKBKB (0.52) | COMTCKS1BSKP2TOP2AIKBKB | |
| Hydrochloric Acid SCHEMBL17868371 | 0.87 | IKBKB (0.52) | COMTCKS1BSKP2TOP2AIKBKB | |
| Hydrochloric Acid SCHEMBL3328059 | 0.87 | IKBKB (0.52) | COMTCKS1BSKP2TOP2AIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160146826-A1 | Electronically Neutral Metal Complexes As Biological Labels | HUNAN SANSURE ACCUCISE BIOTECHNOLOGY CO., LTD. (CN) | 2016-05-26 | — | — | US | disclosed |
| US-9290528-B1 | Light-activated compounds | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | BIO-RAD LABORATORIES, INC. (US) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144046-A1 | CYCLOMETALATED TRANSITION METAL COMPLEXES FOR MULTIPLEX ANALYTE DETECTION | CAD, NCLN, CCL5 | COMT 1939/4885CKS1B 2132/4885SKP2 3303/4885 |
| US-20160146826-A1 | Electronically Neutral Metal Complexes As Biological Labels | MB, MCU, LETM1 | COMT 1964/4885CKS1B 3616/4885SKP2 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.