Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20056396 | 0.90 | TLR8 (0.31) | TLR8 | |
| SCHEMBL13287470 | 0.83 | RAB9A (0.41) | TLR8ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL2792249 | 0.80 | TLR8 (0.46) | TLR8ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL11930756 | 0.79 | LMNA (0.39) | TLR8ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL19033089 | 0.77 | ALDH1A1 (0.37) | TLR8ALDH1A1KMT2APOLBMEN1 | |
| SCHEMBL17219025 | 0.75 | TLR8 (0.49) | TLR8ALDH1A1KMT2APOLB | |
| SCHEMBL11938341 | 0.74 | FPR2 (0.43) | ADORA2BSMN1; SMN2 | |
| SCHEMBL13382183 | 0.73 | MEN1 (0.33) | ALDH1A1KMT2AMEN1L3MBTL1RAB9A | |
| SCHEMBL24810231 | 0.73 | TLR8 (0.34) | TLR8ALDH1A1KMT2APOLBADORA2B | |
| SCHEMBL10363599 | 0.72 | TLR8 (0.50) | TLR8ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065902-A2 | TECHNETIUM- AND RHENIUM-BIS(HETEROARYL) COMPLEXES AND METHODS OF USE THEREOF FOR INHIBITING PSMA | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |