SCHEMBL20056396

SCHEMBL20056396

CCN(Cc1nccn1CCN)Cc1nccn1CCNC

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TLR8 Q9NR97 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13287496 0.90 TLR8 (0.37) TLR8
SCHEMBL13287470 0.75 RAB9A (0.41) TLR8
SCHEMBL2792249 0.72 TLR8 (0.46) TLR8
SCHEMBL11930756 0.71 LMNA (0.39) TLR8
SCHEMBL19033089 0.69 ALDH1A1 (0.37) TLR8
SCHEMBL17219025 0.67 TLR8 (0.49) TLR8
SCHEMBL28712311 0.67 TLR8 (0.45) TLR8
SCHEMBL11938341 0.67 FPR2 (0.43) —
SCHEMBL13382183 0.66 MEN1 (0.33) —
SCHEMBL24810231 0.66 TLR8 (0.34) TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2648766-B1 PSMA-TARGETED DENDRIMERS MOLECULAR INSIGHT PHARM INC (US) 2018-04-18 — — EP disclosed
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