Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 7/20 | 0.42 |
| ▸ | CES1 | P23141 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064572 | 0.82 | CES2 (0.54) | CES2CES1HPGDCYP11B1CYP11B2 | |
| SCHEMBL9847400 | 0.81 | KEAP1 (0.47) | CES2CES1HPGDCA1CA2 | |
| SCHEMBL31258575 | 0.80 | KEAP1 (0.50) | CES2CES1HPGDCYP11B1CYP11B2 | |
| SCHEMBL363928 | 0.80 | KEAP1 (0.50) | CES2CES1HPGDCYP11B1CYP11B2 | |
| SCHEMBL7750943 | 0.80 | CES2 (0.41) | CES2CES1HPGDCYP11B1CYP11B2 | |
| SCHEMBL8611045 | 0.79 | ALDH1A1 (0.52) | HPGDKEAP1NFE2L2POLBMAPT | |
| SCHEMBL13390 | 0.78 | TSHR (0.43) | CES2CES1CYP11B1CYP11B2CA1 | |
| SCHEMBL29470949 | 0.78 | ALDH1A1 (0.50) | CES2CES1HPGDCYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL11035410 | 0.78 | KEAP1 (0.48) | CES2CES1HPGDCYP11B1CYP11B2 | |
| SCHEMBL30753199 | 0.78 | TSHR (0.43) | CES2CES1CYP11B1CYP11B2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104387259-B | One is prepared the method for 2,4,5-trifluoro benzene acetic acid | QUZHOU UNIVERSITY (CN) | 2016-05-04 | — | — | CN | disclosed |
| CN-104387259-A | Method for preparing 2,4,5-trifluorophenylacetic acid | UNIV QUZHOU | 2015-03-04 | — | — | CN | disclosed |
| CN-101981025-A | Diarylmethylamide derivative having antagonistic activity on melanin-concentrating hormone receptor | BANYU PHARMA CO LTD | 2011-02-23 | — | — | CN | disclosed |
| US-7727654-B2 | Membrane of a sulfonated aromatic polymers having polyphenyl and polyphenylene ether units with fluorine and nitrile groups; higher proton conductivity over a wide temperature range, and exhibits superior hot water resistance, chemical stability, toughness and mechanical strength | HONDA MOTOR CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| US-7727654-B2 | Membrane of a sulfonated aromatic polymers having polyphenyl and polyphenylene ether units with fluorine and nitrile groups; higher proton conductivity over a wide temperature range, and exhibits superior hot water resistance, chemical stability, toughness and mechanical strength | HONDA MOTOR CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |