Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.69 |
| ▸ | TNF | P01375 | 1/20 | 0.65 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | PTGIR | P43119 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4277270 | 0.83 | HRH3 (1.00) | HRH3HRH4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17830792 | 0.83 | SMN1; SMN2 (0.71) | ALDH1A1KDM4EATMSMN1; SMN2MEN1 | |
| SCHEMBL25967979 | 0.83 | ALDH1A1 (0.65) | ALDH1A1KDM4EATMSMN1; SMN2MEN1 | |
| SCHEMBL13293708 | 0.81 | HRH3 (0.64) | HRH3HRH4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21884103 | 0.81 | HRH3 (0.65) | HRH3ALDH1A1KDM4EATMSMN1; SMN2 | |
| SCHEMBL5365785 | 0.81 | SIGMAR1 (0.59) | HRH3KDM4EATMSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7468055 | 0.81 | HRH3 (0.95) | HRH3HRH4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11201497 | 0.81 | HRH3 (0.94) | HRH3HRH4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24047167 | 0.80 | HRH3 (0.62) | HRH3HRH4ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL10601850 | 0.80 | SMN1; SMN2 (0.59) | TNFALDH1A1KDM4EATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236911-A1 | LINCOSAMIDE ANTIBIOTICS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-25 | — | — | WO | disclosed |
| WO-2010065782-A1 | METHOD FOR TREATING PULMONARY DISEASES USING RHO KINASE INHIBITOR COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| WO-2009158587-A1 | METHOD FOR TREATING PULMONARY DISEASES USING RHO KINASE INHIBITOR COMPOUNDS | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009155209-A1 | OPHTHALMIC FORMULATION OF RHO KINASE INHIBITOR COMPOUND | INSPIRE PHARMACEUTICALS, INC. (US) | 2009-12-23 | — | — | WO | disclosed |
| WO-2008077057-A2 | CYTOSKELETAL ACTIVE RHO KINASE INHIBITOR COMPOUNDS, COMPOSITION AND USE | INSPIRE PHARMACEUTICALS, INC. (US) | 2008-06-26 | — | — | WO | disclosed |