Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989530 | 0.86 | LMNA (0.83) | ALDH1A1LMNAPOLBSMN1; SMN2ATM | |
| SCHEMBL1045922 | 0.86 | LMNA (0.83) | ALDH1A1LMNAPOLBSMN1; SMN2ATM | |
| SCHEMBL11356824 | 0.86 | LMNA (0.83) | ALDH1A1LMNAPOLBSMN1; SMN2ATM | |
| SCHEMBL7989269 | 0.86 | LMNA (0.83) | ALDH1A1LMNAPOLBSMN1; SMN2ATM | |
| SCHEMBL17830792 | 0.85 | SMN1; SMN2 (0.71) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL18131001 | 0.84 | ALDH1A1 (0.66) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E | |
| SCHEMBL13293323 | 0.83 | HRH3 (0.69) | ALDH1A1SMN1; SMN2ATMKDM4EMEN1 | |
| SCHEMBL10601850 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL10600924 | 0.81 | SMN1; SMN2 (0.61) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL10604885 | 0.81 | SMN1; SMN2 (0.57) | ALDH1A1LMNAPOLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | THE CLEVELAND CLINIC FOUNDATION | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257350-A1 | COMPOUNDS AND METHODS OF PROMOTING OLIGODENDROCYTE PRECURSOR DIFFERENTIATION | CHAT, DCX, GAP43 | ALDH1A1 611/4885LMNA 2149/4885POLB 1214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.