Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542316 | 0.98 | SIGMAR1 (0.51) | SLC6A3SIGMAR1HTR6HRH3CHRM2 | |
| SCHEMBL11620971 | 0.92 | SIGMAR1 (0.54) | SLC6A3SIGMAR1HTR6 | |
| SCHEMBL11542289 | 0.91 | SIGMAR1 (0.53) | SIGMAR1HRH3 | |
| SCHEMBL9304462 | 0.85 | CNR1 (0.50) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL6212322 | 0.83 | HTR6 (0.43) | SIGMAR1HTR6 | |
| SCHEMBL2338975 | 0.81 | HTR6 (0.56) | SIGMAR1HTR6 | |
| SCHEMBL31121639 | 0.81 | HTR6 (0.56) | SIGMAR1HTR6 | |
| SCHEMBL9304524 | 0.79 | SIGMAR1 (0.55) | SIGMAR1HTR6CHRM2CHRM4CHRM5 | |
| SCHEMBL6216413 | 0.78 | HTR6 (0.40) | SIGMAR1HTR6 | |
| SCHEMBL3874874 | 0.77 | HTR6 (0.53) | SIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202222-A2 | Indene derivatives, their preparation and use as medicaments | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-06-30 | — | — | EP | disclosed |