Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304462 | 0.93 | CNR1 (0.50) | SIGMAR1POLBCNR1CHRM2CHRM4 | |
| SCHEMBL11620971 | 0.87 | SIGMAR1 (0.54) | SIGMAR1HTR6 | |
| SCHEMBL11542289 | 0.85 | SIGMAR1 (0.53) | SIGMAR1KMT2AKDM4E | |
| SCHEMBL13297902 | 0.79 | SLC6A3 (0.50) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3868123 | 0.78 | HTR6 (0.53) | SIGMAR1KDM4EHTR6 | |
| SCHEMBL3874874 | 0.78 | HTR6 (0.53) | SIGMAR1KDM4EHTR6 | |
| SCHEMBL11542316 | 0.77 | SIGMAR1 (0.51) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11541639 | 0.77 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL31121639 | 0.74 | HTR6 (0.56) | SIGMAR1HTR6 | |
| SCHEMBL2338975 | 0.74 | HTR6 (0.56) | SIGMAR1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292736-A | Morpholinoalkylindenes as antiglaucoma agents | STERLING WINTHROP INC. (US) | 1994-03-08 | — | — | US | disclosed |