D-Glutamate

D-Glutamate

SCHEMBL1330917

[15NH2][13C@@H]([13CH2][13CH2][13C](=O)O)[13C](=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM8 O00222 2/20 1.00
▸ GRM6 O15303 2/20 1.00
▸ GRM7 Q14831 2/20 1.00
▸ GRM4 Q14833 2/20 1.00
▸ GRIN2D O15399 1/20 1.00
▸ GRIN3B O60391 1/20 1.00
▸ GSR P00390 1/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ GRIK1 P39086 1/20 1.00
▸ GRM5 P41594 1/20 1.00
▸ GRIA1 P42261 1/20 1.00
▸ GRIA2 P42262 1/20 1.00
▸ GRIA3 P42263 1/20 1.00
▸ SLC1A3 P43003 1/20 1.00
▸ SLC1A2 P43004 1/20 1.00
▸ SLC1A1 P43005 1/20 1.00
▸ GRIA4 P48058 1/20 1.00
▸ GRIN1 Q05586 1/20 1.00
▸ GRIN2A Q12879 1/20 1.00
▸ GRIK2 Q13002 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL1554237 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332007 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332297 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL43222 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL2202 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332144 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL410241 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL5704264 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330566 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL931953 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12617847-B2 Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-05-05 — — US disclosed
CN-121090736-A Detection method for identifying small molecular metabolites in plants and application of detection method 青岛百谱生物科技有限公司 2025-12-09 — — CN disclosed
US-11891434-B2 Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 — — US disclosed
EP-4231014-A2 ANTIGEN-BINDING MOLECULE CAPABLE OF BINDING TO PLURALITY OF ANTIGEN MOLECULES REPEATEDLY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-08-23 — — EP disclosed
CN-115932066-A Detection method and application of ultra-high performance liquid phase high resolution mass spectrum non-target metabonomics 上海百趣生物医学科技有限公司 2023-04-07 — — CN disclosed
US-20220187308-A1 ION CONCENTRATION-DEPENDENT BINDING MOLECULE LIBRARY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-06-16 — — US disclosed
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 — — US disclosed
WO-2013121264-A1 SWEET TASTE ENHANCER FRITO-LAY TRADING COMPANY GMBH (CH) 2013-08-22 — — WO disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617847-B2 Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly CD69, CD47, NFATC1 GRM8 1723/4885GRM6 1548/4885GRM7 2839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback