Glutamic Acid

Glutamic Acid

SCHEMBL2202

N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM8 O00222 2/20 1.00
▸ GRM6 O15303 2/20 1.00
▸ GRM7 Q14831 2/20 1.00
▸ GRM4 Q14833 2/20 1.00
▸ GRIN2D O15399 1/20 1.00
▸ GRIN3B O60391 1/20 1.00
▸ GSR P00390 1/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ GRIK1 P39086 1/20 1.00
▸ GRM5 P41594 1/20 1.00
▸ GRIA1 P42261 1/20 1.00
▸ GRIA2 P42262 1/20 1.00
▸ GRIA3 P42263 1/20 1.00
▸ SLC1A3 P43003 1/20 1.00
▸ SLC1A2 P43004 1/20 1.00
▸ SLC1A1 P43005 1/20 1.00
▸ GRIA4 P48058 1/20 1.00
▸ GRIN1 Q05586 1/20 1.00
▸ GRIN2A Q12879 1/20 1.00
▸ GRIK2 Q13002 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL1554237 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332007 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332297 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL43222 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332144 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL410241 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL5704264 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330566 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330917 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL931953 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 1044888 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410494-B1 — — None — — US claimed
US-9976074-B2 Self-suspending proppant particulates using canola protein-based hydrogel HALLIBURTON ENERGY SERVICES, INC. (US) 2018-05-22 — — US claimed
US-9976111-B2 TiN hard mask and etch residual removal VERSUM MATERIALS US, LLC (US) 2018-05-22 — — US claimed
US-9974849-B2 Human Papilloma virus therapeutic vaccine BIOVENTURES, LLC (US) 2018-05-22 — — US claimed
US-9975915-B1 Crystalline forms of nicotinoyl ribosides, modified derivatives thereof, and phosphorylated analogs thereof, and methods of preparation thereof THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2018-05-22 — — US claimed
WO-2018087152-A1 CONCENTRATED ORANGE CARROT PERMEATES GNT GROUP B.V. (NL) 2018-05-17 — — WO claimed
US-20180134677-A1 NOVEL KCNQ POTASSIUM CHANNEL AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2018-05-17 — — US claimed
US-20180133133-A1 STRUCTURED CRYSTALLINE SURFACTANT COMPOSITIONS EVONIK OPERATIONS GMBH (DE) 2018-05-17 — — US claimed
US-20180134742-A1 CRYSTALLINE FORMS OF NICOTINOYL RIBOSIDES, MODIFIED DERIVATIVES THEREOF, AND PHOSPHORYLATED ANALOGS THEREOF, AND METHODS OF PREPARATION THEREOF THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2018-05-17 — — US claimed
US-20180135085-A1 AMINO ACID PRODUCTION EVONIK DEGUSSA GMBH (DE) 2018-05-17 — — US claimed
US-3966749-A Novel synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols, the pharmaceutically acceptable acid addition salts thereof and intermediate useful in the preparation thereof INTERX RESEARCH CORPORATION (US) 1976-06-29 — — US claimed
US-3963579-A Microbiological process for the production of pepstatins SANRAKU-OCEAN CO., LTD. (JA) 1976-06-15 — — US claimed
US-3960476-A OXIDATION BASE GHILARDI GIULIANA 1976-06-01 — — US claimed
US-3958581-A Cosmetic composition containing a cationic polymer and divalent metal salt for strengthening the hair L'OREAL (FR) 1976-05-25 — — US claimed
US-3956481-A Hydrosoluble extracts of mycobacteria, their preparation and use AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1976-05-11 — — US claimed
US-3956040-A Explosive slurry composition containing sodium montmorillonite GELAN KABUSHIKI KAISHA (JA) 1976-05-11 — — US claimed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 — — US claimed
US-3950555-A Method of tenderizing and improving the flavor of food STROMBERG BENGT 1976-04-13 — — US claimed
US-3939042-A FERMENTATION OF PSEUDOMONAS OR PROTAMINOBACTER KYOWA HAKKO KOGYO CO., LTD. (JA) 1976-02-17 — — US claimed
US-3933783-A Formation of peptide bonds in the presence of isonitriles AJINOMOTO CO., INC. (JA) 1976-01-20 — — US claimed
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