D-Glutamate

D-Glutamate

SCHEMBL43222

N[C@H](CCC(=O)O)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRM8 O00222 2/20 1.00
▸ GRM6 O15303 2/20 1.00
▸ GRM7 Q14831 2/20 1.00
▸ GRM4 Q14833 2/20 1.00
▸ GRIN2D O15399 1/20 1.00
▸ GRIN3B O60391 1/20 1.00
▸ GSR P00390 1/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ GRIK1 P39086 1/20 1.00
▸ GRM5 P41594 1/20 1.00
▸ GRIA1 P42261 1/20 1.00
▸ GRIA2 P42262 1/20 1.00
▸ GRIA3 P42263 1/20 1.00
▸ SLC1A3 P43003 1/20 1.00
▸ SLC1A2 P43004 1/20 1.00
▸ SLC1A1 P43005 1/20 1.00
▸ GRIA4 P48058 1/20 1.00
▸ GRIN1 Q05586 1/20 1.00
▸ GRIN2A Q12879 1/20 1.00
▸ GRIK2 Q13002 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL1554237 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332007 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332297 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL2202 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1332144 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL410241 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL5704264 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330566 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL1330917 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL931953 1.00 GRM8 (1.00) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15594 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746912-A1 ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES Simris Biologics GmbH (DE) 2026-05-27 — — EP claimed
CN-122081345-A Engineering strain for synthesizing gamma-poly-L-glutamic acid and application thereof — 2026-05-26 — — CN claimed
CN-122081285-A Broad-spectrum polyglutamic acid degrading enzyme and application thereof in preparation of low-molecular-weight polyglutamic acid — 2026-05-26 — — CN claimed
CN-122074077-A Radiolabeled melanocortin 1 receptor-specific alpha-melanocyte stimulating hormone analogs for imaging or therapy 省卫生服务机构 2026-05-22 — — CN claimed
EP-4745153-A1 GLP-1, GIP AND GCG RECEPTOR TRIAGONIST AND USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-05-20 — — EP claimed
CN-122070294-A Stable vitreous material based on histidine, arginine and glutamic acid amino acids 阵序补丁有限公司 2026-05-19 — — CN claimed
US-12630520-B2 Left-handed bicyclic morpholine and salt thereof, preparation method therefor, pharmaceutical composition, and use INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2026-05-19 — — US claimed
US-12630588-B2 Bicyclic peptide ligands specific for CD137 BICYCLETX LIMITED (GB) 2026-05-19 — — US claimed
WO-2026100725-A1 ANTI-CCR8 ANTIBODY AND ANTIBODY-DRUG CONJUGATE THEREOF 住友ファーマ株式会社 2026-05-15 — — WO claimed
US-20260131015-A1 NEODEGRADER CONJUGATES ORUM THERAPEUTICS INC (KR) 2026-05-14 — — US claimed
US-4127524-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127525-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127523-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127534-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127535-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127537-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127536-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127530-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127531-A ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
US-4127528-A HEXADECAPEPTIDE, ANALGESIC VETERANS ADMINISTRATION, THE UNITED STATES OF AMERICA AS REPRESENTED BY 1978-11-28 — — US claimed
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