Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923002 | 0.95 | MAPT (0.57) | MAPTTP53LMNACRHBPCRHR2 | |
| SCHEMBL5923381 | 0.92 | MAPT (0.55) | MAPTTP53LMNAALDH1A1KMT2A | |
| SCHEMBL5923063 | 0.91 | MAPT (0.54) | MAPTTP53ALDH1A1KMT2AGLA | |
| SCHEMBL5923088 | 0.84 | MAPT (0.48) | MAPTTP53LMNAALDH1A1KMT2A | |
| SCHEMBL5923283 | 0.82 | MAPT (0.58) | MAPTCRHBPCRHR2ALDH1A1KMT2A | |
| SCHEMBL5923110 | 0.80 | S1PR1 (0.46) | MAPTTP53ALDH1A1HSD17B10KDM4E | |
| SCHEMBL5923278 | 0.80 | ALDH1A1 (0.49) | MAPTLMNACRHBPCRHR2ALDH1A1 | |
| SCHEMBL12443467 | 0.79 | MEN1 (0.48) | LMNAKMT2ARAB9AMEN1NPC1 | |
| SCHEMBL12588560 | 0.79 | RAB9A (0.60) | TP53LMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL5923253 | 0.78 | RAB9A (0.51) | MAPTLMNACRHBPCRHR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260108604-A1 | CAR T CELL COMPOSITIONS FOR TREATMENT OF CANCER | WASHINGTON UNIVERSITY (US) | 2026-04-23 | — | — | US | disclosed |
| WO-2024059821-A2 | CAR T CELL COMPOSITIONS FOR TREATMENT OF CANCER | WASHINGTON UNIVERSITY (US) | 2024-03-21 | — | — | WO | disclosed |
| US-8445677-B2 | Substituted pyrimidyl guanidine derivatives having anticancer activity | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-05-21 | — | — | US | disclosed |
| US-8445677-B2 | Substituted pyrimidyl guanidine derivatives having anticancer activity | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2013-05-21 | — | — | US | disclosed |
| US-20100160313-A1 | DISCOVERY OF NOVEL ANTICANCER COMPOUNDS BASED ON CONFORMATIONAL SAMPLING OF QUINOXALINHYDRAZIDE PHARMACOPHORE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-06-24 | — | — | US | disclosed |
| US-20100160313-A1 | DISCOVERY OF NOVEL ANTICANCER COMPOUNDS BASED ON CONFORMATIONAL SAMPLING OF QUINOXALINHYDRAZIDE PHARMACOPHORE | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160313-A1 | DISCOVERY OF NOVEL ANTICANCER COMPOUNDS BASED ON CONFORMATIONAL SAMPLING OF QUINOXALINHYDRAZIDE PHARMACOPHORE | ABCG2, NQO2, TOP1 | MAPT 4028/4885TP53 93/4885LMNA 3912/4885 |
| US-20260108604-A1 | CAR T CELL COMPOSITIONS FOR TREATMENT OF CANCER | FOXO3, FOXO1, NFATC1 | MAPT 2337/4885TP53 7/4885LMNA 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.