SCHEMBL13311684

SCHEMBL13311684

CN(C)CCOc1ccccc1N1C(=O)C2C(C1=O)[C@H]1CC[C@@H]2O1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
HTR7 P34969 3/20 0.43
ALDH1A1 P00352 5/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
KDM4E B2RXH2 3/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.40
HTR1B P28222 1/20 0.40
RAB9A P51151 2/20 0.39
DRD2 P14416 1/20 0.39
DRD1 P21728 1/20 0.39
DRD4 P21917 1/20 0.39
DRD5 P21918 1/20 0.39
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3495027 0.79 L3MBTL1 (0.67) L3MBTL1ALDH1A1SMN1; SMN2KDM4EKMT2A
SCHEMBL13311673 0.79 CACNA1B (0.44) L3MBTL1ALDH1A1SMN1; SMN2MAPTGAA
SCHEMBL6559707 0.74 HTR7 (0.46) HTR7ALDH1A1SMN1; SMN2KDM4EHTR1B
SCHEMBL3497134 0.72 L3MBTL1 (1.00) L3MBTL1ALDH1A1SMN1; SMN2KMT2AMEN1
SCHEMBL7944255 0.70 FADS1 (0.45) HTR7ALDH1A1SMN1; SMN2KDM4EHTR1B
SCHEMBL3496324 0.69 L3MBTL1 (0.68) L3MBTL1ALDH1A1KMT2AMEN1MAPT
SCHEMBL3191299 0.66 TSHR (0.66) L3MBTL1ALDH1A1KDM4EKMT2AMEN1
SCHEMBL3191276 0.66 TSHR (0.66) L3MBTL1ALDH1A1KDM4EKMT2AMEN1
SCHEMBL15836588 0.65 MEN1 (0.65) L3MBTL1ALDH1A1KMT2AMEN1GAA
SCHEMBL3495788 0.65 MEN1 (0.65) L3MBTL1ALDH1A1KMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2010-06-03 US disclosed
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS PPP1R10, TASP1, PPP5C L3MBTL1 598/4885HTR7 3728/4885ALDH1A1 3457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.