Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 5/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15646819 | 0.92 | UCHL1 (0.49) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL30147617 | 0.83 | UCHL1 (0.61) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL20571008 | 0.83 | UCHL1 (0.61) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL2885604 | 0.83 | UCHL1 (0.47) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL20571049 | 0.81 | UCHL1 (0.46) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL26100463 | 0.81 | UCHL1 (0.48) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL3133623 | 0.80 | L3MBTL1 (0.39) | UCHL1KDM1ANOTUMBRD4MPO | |
| SCHEMBL2885921 | 0.80 | NOTUM (0.47) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL3502782 | 0.80 | UCHL1 (0.45) | UCHL1KDM1AHDAC1HDAC6NOTUM | |
| SCHEMBL22048927 | 0.79 | HDAC1 (0.51) | UCHL1KDM1AHDAC1HDAC6NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | UCHL1 2478/4885KDM1A 3273/4885HDAC1 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.