Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 5/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312492 | 0.93 | PTGER4 (0.53) | PTGER2PTGER4FFAR1FFAR4POLB | |
| SCHEMBL13312462 | 0.91 | FFAR1 (0.46) | PTGER2PTGER4FFAR1FFAR4RXRA | |
| SCHEMBL13312487 | 0.91 | PTGER4 (0.43) | PTGER2PTGER4FFAR1FFAR4ALDH1A1 | |
| SCHEMBL13312482 | 0.91 | FFAR1 (0.47) | PTGER2PTGER4FFAR1FFAR4ALDH1A1 | |
| SCHEMBL13312479 | 0.91 | FFAR1 (0.44) | PTGER2PTGER4FFAR1FFAR4ALDH1A1 | |
| SCHEMBL13348240 | 0.89 | PTGER2 (0.49) | PTGER2PTGER4TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL13312475 | 0.88 | FFAR1 (0.43) | PTGER2PTGER4FFAR1FFAR4ALDH1A1 | |
| SCHEMBL13312496 | 0.87 | PTGER4 (0.61) | PTGER2PTGER4FFAR1FFAR4POLB | |
| SCHEMBL13312484 | 0.86 | PTGER4 (0.45) | PTGER2PTGER4FFAR1FFAR4RXRA | |
| SCHEMBL13312059 | 0.86 | RXRA (0.48) | PTGER2PTGER4FFAR1FFAR4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PTGER2 3346/4885PTGER4 1432/4885FFAR1 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.