Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 5/20 | 0.49 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312477 | 0.89 | PTGER2 (0.51) | PTGER2PTGER4SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13348283 | 0.86 | ALDH1A1 (0.46) | PTGER2PTGER4ALDH1A1KMT2AMEN1 | |
| SCHEMBL13348138 | 0.85 | HPD (0.41) | PTGER2PTGER4SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL13348170 | 0.84 | PTGER4 (0.39) | PTGER2PTGER4SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13348407 | 0.84 | FFAR1 (0.38) | PTGER2PTGER4ALDH1A1KMT2AMEN1 | |
| SCHEMBL13312492 | 0.82 | PTGER4 (0.53) | PTGER2PTGER4SMN1; SMN2RAB9ALMNA | |
| SCHEMBL13348045 | 0.81 | DRD2 (0.39) | PTGER2PTGER4TSHRALDH1A1KMT2A | |
| SCHEMBL13312487 | 0.80 | PTGER4 (0.43) | PTGER2PTGER4ALDH1A1KMT2AMEN1 | |
| SCHEMBL13312462 | 0.80 | FFAR1 (0.46) | PTGER2PTGER4RAB9A | |
| SCHEMBL13312482 | 0.80 | FFAR1 (0.47) | PTGER2PTGER4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PTGER2 3346/4885PTGER4 1432/4885SMN1; SMN2 4313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.