SCHEMBL13312561

SCHEMBL13312561

O=C(O)CCc1ccc(OCc2cccc3c2N(S(=O)(=O)c2ccccc2C(F)(F)F)CC3)cc1F

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.41
FFAR4 Q5NUL3 5/20 0.41
RXRA P19793 1/20 0.40
RXRB P28702 1/20 0.40
RXRG P48443 1/20 0.40
RORC P51449 1/20 0.39
PTGER2 P43116 2/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
PTGER4 P35408 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13312566 0.91 FFAR1 (0.44) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312563 0.88 FFAR1 (0.50) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312560 0.88 FFAR1 (0.44) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312569 0.88 FFAR1 (0.45) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312546 0.87 PTGER2 (0.48) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312567 0.87 FFAR1 (0.44) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312550 0.86 RORC (0.46) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312554 0.85 RORC (0.55) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312469 0.84 FFAR1 (0.41) FFAR1FFAR4RXRARXRBRXRG
SCHEMBL13312549 0.84 TUBB4A (0.48) FFAR1FFAR4RXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100152165-A1 CARBOXYLIC ACID DERIVATIVES ASTELLAS PHARMA INC. (JP) 2010-06-17 US disclosed
US-20100152165-A1 CARBOXYLIC ACID DERIVATIVES ASTELLAS PHARMA INC. (JP) 2010-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152165-A1 CARBOXYLIC ACID DERIVATIVES GPR119, GPR65, HCAR1 FFAR1 14/4885FFAR4 15/4885RXRA 475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.