Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | DRD3 | P35462 | 6/20 | 0.37 |
| ▸ | AGER | Q15109 | 11/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1283718 | 0.90 | DRD2 (0.44) | DRD2DRD3AGERCASRADORA2A | |
| SCHEMBL1283630 | 0.84 | DRD2 (0.46) | DRD2DRD3AGER | |
| SCHEMBL1283521 | 0.83 | KMT2A (0.40) | DRD2DRD3AGER | |
| SCHEMBL1283201 | 0.83 | DRD3 (0.48) | DRD2DRD3AGER | |
| SCHEMBL1283300 | 0.82 | KDM4E (0.48) | DRD2DRD3AGERCASR | |
| SCHEMBL1283150 | 0.81 | DRD3 (0.50) | DRD2DRD3AGERCASR | |
| SCHEMBL1283251 | 0.81 | DRD3 (0.47) | DRD2DRD3AGERCASR | |
| SCHEMBL1282704 | 0.81 | AGER (0.48) | DRD2DRD3AGERCASR | |
| SCHEMBL13372539 | 0.80 | DRD3 (0.49) | DRD2DRD3AGERCASR | |
| SCHEMBL1614125 | 0.80 | DRD3 (0.54) | DRD2DRD3AGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737285-B2 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | TRANSTECH PHARMA, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-7737285-B2 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | TRANSTECH PHARMA, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20070213347-A1 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | TRANSTECH PHARMA (US) | 2007-09-13 | — | — | US | disclosed |
| US-20070213347-A1 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | TRANSTECH PHARMA (US) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213347-A1 | Azole derivatives and fused bicyclic azole derivatives as therapeutic agents | AGER, S100A4, S100B | DRD2 4691/4885DRD3 4321/4885AGER 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.