Sugi Predict

Sugi Predict / Compounds / SCHEMBL133154

SCHEMBL133154

SCHEMBL133154

[CH2]C1=Cc2cccc3cccc1c23

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 4/20 0.52
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ MAPT P10636 3/20 0.52
▸ ALDH1A1 P00352 6/20 0.44
▸ CES2 O00748 1/20 0.44
▸ BCHE P06276 1/20 0.44
▸ CES1 P23141 1/20 0.44
▸ MCL1 Q07820 1/20 0.44
▸ HSD17B10 Q99714 5/20 0.42
▸ TSHR P16473 3/20 0.42
▸ ATM Q13315 2/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ S100A4 P26447 1/20 0.41
▸ PABPC1 P11940 3/20 0.39
▸ CASP1 P29466 2/20 0.39
▸ CASP7 P55210 2/20 0.39
▸ CYP3A4 P08684 2/20 0.39
▸ DNMT1 P26358 2/20 0.39
▸ HPGD P15428 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28962436 0.76 MAPK1 (0.55) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL131080 0.76 MAPK1 (0.55) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL133155 0.73 MEN1 (0.52) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL4073489 0.73 MAPK1 (0.74) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL7557528 0.73 MAPK1 (0.52) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL130420 0.73 KMT2A (0.59) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL131079 0.73 MAPK1 (0.52) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL58539 0.73 MAPK1 (0.57) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL3289050 0.73 MAPK1 (0.52) MAPK1MEN1KMT2AMAPTALDH1A1
SCHEMBL4507358 0.73 MAPK1 (0.52) MAPK1MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0642530-B1 DERIVATIVES OF DOLASTATIN BASF AG (DE) 1998-08-12 — — EP claimed
US-5502032-A SYNTHETIC OLIGOPEPTIDES, ANTITUMOR, ANTICANCER BASF AKTIENGESELLSCHAFT (DE) 1996-03-26 — — US claimed
EP-0674652-A1 DOLOSTATIN ANALOG BASF AKTIENGESELLSCHAFT (DE) 1995-10-04 — — EP claimed
EP-0642530-A1 DERIVATIVES OF DOLASTATIN BASF Aktiengesellschaft (DE) 1995-03-15 — — EP claimed
WO-1994013695-A1 DOLOSTATIN ANALOG BASF AKTIENGESELLSCHAFT (DE) 1994-06-23 — — WO claimed
WO-1993023424-A1 DERIVATIVES OF DOLASTATIN BASF AKTIENGESELLSCHAFT (DE) 1993-11-25 — — WO claimed
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2024-02-29 — — US disclosed
US-11805779-B2 Plant disease control composition and method for controlling plant disease by applying the same MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-11-07 — — US disclosed
US-20210000112-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS AGRO, INC. (JP) 2021-01-07 — — US disclosed
US-10806141-B2 Plant disease control composition and method for controlling plant disease by applying the same MITSUI CHEMICALS AGRO, INC. (JP) 2020-10-20 — — US disclosed
EP-3263109-B1 DRUG FOR PREVENTING AND/OR TREATING DEMENTIA NAT UNIV CORP TOTTORI UNIV (JP) 2020-06-17 — — EP disclosed
US-10428019-B2 Chiral auxiliaries WAVE LIFE SCIENCES LTD. (SG) 2019-10-01 — — US disclosed
US-10413546-B2 Drug for preventing and/or treating dementia NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY (JP) 2019-09-17 — — US disclosed
EP-0642530-B1 DERIVATIVES OF DOLASTATIN BASF AG (DE) 1998-08-12 — — EP disclosed
US-5502032-A SYNTHETIC OLIGOPEPTIDES, ANTITUMOR, ANTICANCER BASF AKTIENGESELLSCHAFT (DE) 1996-03-26 — — US disclosed
EP-0674652-A1 DOLOSTATIN ANALOG BASF AKTIENGESELLSCHAFT (DE) 1995-10-04 — — EP disclosed
EP-0642530-A1 DERIVATIVES OF DOLASTATIN BASF Aktiengesellschaft (DE) 1995-03-15 — — EP disclosed
WO-1994013695-A1 DOLOSTATIN ANALOG BASF AKTIENGESELLSCHAFT (DE) 1994-06-23 — — WO disclosed
WO-1993023424-A1 DERIVATIVES OF DOLASTATIN BASF AKTIENGESELLSCHAFT (DE) 1993-11-25 — — WO disclosed
EP-0562832-A1 Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use SANKYO COMPANY LIMITED (JP) 1993-09-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, HAX1, BROX MAPK1 3492/4885MEN1 1867/4885KMT2A 1298/4885
US-10806141-B2 Plant disease control composition and method for controlling plant disease by applying the same SNX1, HAX1, BROX MAPK1 3521/4885MEN1 1880/4885KMT2A 1329/4885
US-10428019-B2 Chiral auxiliaries PCNA, POLL, TYMP MAPK1 3683/4885MEN1 1480/4885KMT2A 3540/4885
US-10413546-B2 Drug for preventing and/or treating dementia XDH, ACHE, DDO MAPK1 1503/4885MEN1 3422/4885KMT2A 2718/4885
US-11805779-B2 Plant disease control composition and method for controlling plant disease by applying the same SNX1, HAX1, BROX MAPK1 3492/4885MEN1 1867/4885KMT2A 1298/4885
US-20210000112-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, HAX1, BROX MAPK1 3492/4885MEN1 1867/4885KMT2A 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.